Evidence map›Paper›PMID 38932254›Full record

ArticleViruses2024

Human Immunodeficiency Virus Type-1 Genetic Diversity and Drugs Resistance Mutations among People Living with HIV in Karachi, Pakistan.

Abdur Rashid, Li Kang, Feng Yi, Qingfei Chu, Sharaf Ali Shah, Syed Faisal Mahmood, Yimam Getaneh, Min Wei, Song Chang, Syed Hani Abidi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdur RashidSchool of Medicine, Nankai University, Tianjin 300071, China.ORCID 0000-0002-4539-5320
Li KangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Feng YiNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Qingfei ChuNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Sharaf Ali ShahBridge Consultants Foundation, Karachi 75100, Pakistan.
Syed Faisal MahmoodDepartment of Medicine, Aga Khan University, Karachi 74800, Pakistan.ORCID 0000-0002-3390-7659
Yimam GetanehState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.ORCID 0000-0002-8222-0132
Min WeiSchool of Medicine, Nankai University, Tianjin 300071, China.
Song ChangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Syed Hani AbidiDepartment of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.ORCID 0000-0001-9497-0902
Yiming ShaoSchool of Medicine, Nankai University, Tianjin 300071, China.ORCID 0000-0002-9416-190X

Funding

National Natural Science Foundation International/Inter-Organization Cooperation and Exchange Study-NSFC-VR Project (China and Switzerland) 81861138011
6 · The paper itself

Abstract

The human immunodeficiency virus type-1 epidemic in Pakistan has significantly increased over the last two decades. In Karachi, Pakistan, there is a lack of updated information on the complexity of HIV-1 genetic diversity and the burden of drug resistance mutations (DRMs) that can contribute to ART failure and poor treatment outcomes. This study aimed to determine HIV-1 genetic diversity and identify drug-resistance mutations among people living with HIV in Karachi. A total of 364 HIV-positive individuals, with a median age of 36 years, were enrolled in the study. The HIV-1 partial

Indexed as

Anti-HIV AgentsDrug Resistance, ViralGenetic VariationHIV-1HIV InfectionsMutationPhylogenyAdolescentAdultFemaleGenotypeHumansMaleMiddle AgedPakistanYoung AdultAnti-HIV Agentsantiretroviral therapydrug resistancegenetic diversityHIV-1KarachiPakistanphylogeny

Identifiers

PMID38932254
PMCPMC11209141

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.