ReviewViruses2024
Recombination of Porcine Reproductive and Respiratory Syndrome Virus: Features, Possible Mechanisms, and Future Directions.
Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Pathogenicity and virulence of PRRSV: From regulated cell death reprogramming landscape and immune subversion to precision vaccinology.Virulence · 2026Review
- Article
- Molecular Epidemiology, Phylogeography, and Recombination Dynamics of PRRSV-2 Sublineage L1C in Mainland China.Viruses · 2026Article
- Establishment of an Indirect ELISA Detection Method for Porcine Reproductive and Respiratory Syndrome Virus NSP10.Veterinary sciences · 2026Article
- CRISPR mediated PRRS resistant pigs: biological success, welfare implications, and ethical regulatory challenges for sustainable swine production.Porcine health management · 2026Review
- Structural basis of porcine reproductive and respiratory syndrome virus 2 neutralization by a GP4-targeting monoclonal antibody.The Journal of general virology · 2026Article
- Phylogenetic Lineages of PRRSV-2 from Canada Reveal Patterns of Transboundary Spread and Two Novel Sub-Lineages in North America.Pathogens (Basel, Switzerland) · 2026Article
- Molecular epidemiology and genetic evolution of PRRSV ORF5 in Sichuan, Southwest China.Frontiers in microbiology · 2026Article
- Article
- Viral Vaccines as an Alternative to Antimicrobials: A Perspective from Swine Veterinarians on Challenges, Opportunities, and Future Directions.Pathogens (Basel, Switzerland) · 2025Article
- Galectin 3-binding protein suppresses PRRSV replication via Cullin3-mediated ubiquitination degradation of non-structural protein 12.Journal of virology · 2025Article
- Ipriflavone Inhibits Porcine Reproductive and Respiratory Syndrome Virus Infection via RIG-I/IRF3-Mediated Interferon Signaling.Animals : an open access journal from MDPI · 2025Article
- Next-Generation Sequencing Reveals Field Strain Dynamics and PRRSV-2 Clearance in Gilts When Using Tylvalosin During MLV Vaccination.Vaccines · 2025Article
- Molecular characterization of porcine reproductive and respiratory syndrome virus in Henan and Shanxi, China, during 2023-2024.Archives of virology · 2025Article
- Recombinants Are the Key Drivers of Recent PRRSV-2 Evolution.Pathogens (Basel, Switzerland) · 2025Article
- Article
- Genome and Pathogenicity Analysis of an NADC30-like PRRSV Strain in China's Xinjiang Province.Viruses · 2025Article
- Evaluation of the utility of testicular-only processing fluid for porcine reproductive and respiratory syndrome virus diagnostics and the effect of sample pooling on the test results.Journal of veterinary research · 2025Article
- Getah Virus: A New Contaminant in Veterinary Vaccines.Veterinary sciences · 2025Article
- Lineage 7 Porcine Reproductive and Respiratory Syndrome Vaccine Demonstrates Cross-Protection Against Lineage 1 and Lineage 3 Strains.Vaccines · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Recombination is a pervasive phenomenon in RNA viruses and an important strategy for accelerating the evolution of RNA virus populations. Recombination in the porcine reproductive and respiratory syndrome virus (PRRSV) was first reported in 1999, and many case reports have been published in recent years. In this review, all the existing reports on PRRSV recombination events were collected, and the genotypes, parental strains, and locations of the recombination breakpoints have been summarized and analyzed. The results showed that the recombination pattern constantly changes; whether inter- or intra-lineage recombination, the recombination hotspots vary in different recombination patterns. The virulence of recombinant PRRSVs was higher than that of the parental strains, and the emergence of virulence reversion was caused by recombination after using MLV vaccines. This could be attributed to the enhanced adaptability of recombinant PRRSV for entry and replication, facilitating their rapid propagation. The aim of this paper was to identify common features of recombinant PRRSV strains, reduce the recombination risk, and provide a foundation for future research into the mechanism of PRRSV recombination.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.