Evidence map›Paper›PMID 38932186›Full record

ArticleViruses2024

Exploring the Epidemiological Surveillance of Hepatitis A in South Africa: A 2023 Perspective.

Keveshan Bhagwandin, Jayendrie Thaver-Kleitman, Kathleen Subramoney, Morubula Jack Manamela, Nishi Prabdial-Sing

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keveshan BhagwandinDivision of the National Health Laboratory Services, National Institute for Communicable Diseases, Johannesburg 2131, South Africa.
Jayendrie Thaver-KleitmanDivision of the National Health Laboratory Services, National Institute for Communicable Diseases, Johannesburg 2131, South Africa.
Kathleen SubramoneyDivision of the National Health Laboratory Services, National Institute for Communicable Diseases, Johannesburg 2131, South Africa.ORCID 0000-0001-6037-9890
Morubula Jack ManamelaDivision of the National Health Laboratory Services, National Institute for Communicable Diseases, Johannesburg 2131, South Africa.
Nishi Prabdial-SingDivision of the National Health Laboratory Services, National Institute for Communicable Diseases, Johannesburg 2131, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis A (HAV) presents a significant global health concern with diverse clinical manifestations primarily transmitted through fecal-oral routes, emphasizing the critical role of sanitation and water cleanliness in transmission dynamics. Age-related variations, notably asymptomatic presentation in children, add complexity. The World Health Organization's (WHO) endemicity classification aids in understanding prevalence and control strategies. This study examines 2023 South African epidemiological data on HAV cases, evaluating age distribution, incidence rates, and provincial disparities. Data from the national surveillance system and weather services were analyzed. Findings reveal distinct age-related trends, with the highest seroprevalence observed in the 5-9 age group with the most burdened areas located in the Western Cape, KwaZulu-Natal, and Gauteng provinces. Furthermore, seasonal rainfall variations correlate with increased incidence in Western Cape and KZN. The amalgamation of results suggest a potential epidemiological shift, emphasizing the need for updated immunization strategies. Noteworthy patterns, like the rise in 5-9-year-olds, may be influenced by factors such as school clustering and migration. Provincial disparities and the impact of climatic events underscore the necessity for dynamic vaccination strategies and surveillance network enhancements. This study highlights the urgency for improved understanding and response to HAV in South Africa.

Indexed as

Hepatitis AAdolescentAdultAgedAge DistributionChildChild, PreschoolEpidemiological MonitoringFemaleHumansIncidenceInfantInfant, NewbornMaleMiddle AgedPrevalenceendemicityhepatitis ANMCSSSDWsurveillance

Identifiers

PMID38932186
PMCPMC11209128

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.