Evidence map›Paper›PMID 38932174›Full record

ReviewViruses2024

Molecular Markers and Mechanisms of Influenza A Virus Cross-Species Transmission and New Host Adaptation.

Xinyi Guo, Yang Zhou, Huijun Yan, Qing An, Chudan Liang, Linna Liu, Jun Qian

Abstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  13. Deliberating the scientific evidence base for influenza transmission to raw milk consumers.Risk analysis : an official publication of the Society for Risk Analysis · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinyi GuoSchool of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.
Yang ZhouGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510440, China.
Huijun YanZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Qing AnCollege of Wildlife and Protected Area, Northeast Forestry University, Harbin 150040, China.
Chudan LiangZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Linna LiuGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510440, China.ORCID 0000-0003-4122-9998
Jun QianSchool of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.

Funding

Science and Technology Planning Project of Guangdong Province, China;Basic Research Program of Guangzhou Municipal Science and Technology Bureau 2022B1111010004;SL2023A03J01074
6 · The paper itself

Abstract

Influenza A viruses continue to be a serious health risk to people and result in a large-scale socio-economic loss. Avian influenza viruses typically do not replicate efficiently in mammals, but through the accumulation of mutations or genetic reassortment, they can overcome interspecies barriers, adapt to new hosts, and spread among them. Zoonotic influenza A viruses sporadically infect humans and exhibit limited human-to-human transmission. However, further adaptation of these viruses to humans may result in airborne transmissible viruses with pandemic potential. Therefore, we are beginning to understand genetic changes and mechanisms that may influence interspecific adaptation, cross-species transmission, and the pandemic potential of influenza A viruses. We also discuss the genetic and phenotypic traits associated with the airborne transmission of influenza A viruses in order to provide theoretical guidance for the surveillance of new strains with pandemic potential and the prevention of pandemics.

Indexed as

Host AdaptationInfluenza A virusInfluenza, HumanAnimalsBirdsHumansInfluenza in BirdsPandemicsadaptive mutationscross-species transmissioninfluenza A virusmolecular mechanismsreassortment

Identifiers

PMID38932174
PMCPMC11209369

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.