Evidence map›Paper›PMID 38932167›Full record

ArticleViruses2024

Clinical Factors Associated with SFTS Diagnosis and Severity in Cats.

Hiromu Osako, Qiang Xu, Takeshi Nabeshima, Jean Claude Balingit, Khine Mya Nwe, Fuxun Yu, Shingo Inoue, Daisuke Hayasaka, Mya Myat Ngwe Tun, Kouichi Morita and 1 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hiromu OsakoDepartment of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki 852-8523, Japan.
Qiang XuDepartment of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki 852-8523, Japan.
Takeshi NabeshimaDepartment of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki 852-8523, Japan.
Jean Claude BalingitDepartment of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki 852-8523, Japan.ORCID 0000-0002-2165-907X
Khine Mya NweDepartment of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki 852-8523, Japan.
Fuxun YuDepartment of Central Laboratory, Guizhou Provincial People's Hospital, Guiyang 550002, China.ORCID 0000-0001-8804-2755
Shingo InoueKenya Research Station, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki 852-8523, Japan.
Daisuke HayasakaJoint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi 753-8515, Japan.
Mya Myat Ngwe TunDepartment of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki 852-8523, Japan.ORCID 0000-0002-8986-6307
Kouichi MoritaDepartment of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki 852-8523, Japan.
Yuki TakamatsuDepartment of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki 852-8523, Japan.ORCID 0009-0008-6706-438X

Funding

Japan Agency for Medical Research and Development JP23fm0208101, JP23fk0108656, JP23wm0125006, JP22wm0325023, JP22fm0208101, JP21fm0208101, JP21wm0325023, and JP20wm0323023Japan Society for the Promotion of Science 21K07059 and 22KK0115Joint/Research Center on Tropical Disease, Institute of Tropical Medicine, Nagasaki University 2022-Ippan-12 and 2023-Ippan-16
6 · The paper itself

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is a potentially fatal tick-borne zoonosis caused by SFTS virus (SFTSV). In addition to tick bites, animal-to-human transmission of SFTSV has been reported, but little is known about feline SFTSV infection. In this study, we analyzed data on 187 cats with suspected SFTS to identify biomarkers for SFTS diagnosis and clinical outcome. Body weight, red and white blood cell and platelet counts, and serum aspartate aminotransferase and total bilirubin levels were useful for SFTS diagnosis, whereas alanine aminotransferase, aspartate aminotransferase and serum SFTSV RNA levels were associated with clinical outcome. We developed a scoring model to predict SFTSV infection. In addition, we performed a phylogenetic analysis to reveal the relationship between disease severity and viral strain. This study provides comprehensive information on feline SFTS and could contribute to the protection of cat owners, community members, and veterinarians from the risk of cat-transmitted SFTSV infection.

Indexed as

Cat DiseasesPhlebovirusPhylogenySevere Fever with Thrombocytopenia SyndromeAlanine TransaminaseAnimalsAspartate AminotransferasesBiomarkersCatsFemaleMaleRNA, ViralSeverity of Illness IndexAlanine TransaminaseAspartate AminotransferasesBiomarkersRNA, Viralbiomarkerscatprognosis factorssevere fever thrombocytopenia syndromeveterinarian

Identifiers

PMID38932167
PMCPMC11209305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.