Evidence map›Paper›PMID 38932152›Full record

ArticleViruses2024

Analysis of Replication, Cell Division-Mediated Spread, and HBV Envelope Protein-Dependent Pseudotyping of Three Mammalian Delta-like Agents.

Gnimah Eva Gnouamozi, Zhenfeng Zhang, Vibhu Prasad, Chris Lauber, Stefan Seitz, Stephan Urban

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gnimah Eva GnouamoziDepartment of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0009-0006-6034-400X
Zhenfeng ZhangDepartment of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-0013-3685
Vibhu PrasadDepartment of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0001-7450-607X
Chris LauberInstitute for Experimental Virology, TWINCORE Centre for Experimental and Clinical Infection Research, a Joint Venture between the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI), 30625 Hannover, Germany.
Stefan SeitzGerman Center for Infection Research (DZIF), Heidelberg Partner Site, 69120 Heidelberg, Germany.
Stephan UrbanDepartment of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0003-1560-8038

Funding

Deutsche Forschungsgemeinschaft 272983813Deutsche Forschungsgemeinschaft 390874280European Molecular Biology Organization ALTF 454-2020German Center for Infection Research TTU 05.904, TTU 05.807, TTU 05.804, TTU 05.704.National Natural Science Foundation of China 32370167Virological and Immunological determinants od COVID-19 pathogenesis - lessons to get prepared for future pandemics KA1-Co-02 "CoViPa"
6 · The paper itself

Abstract

The human hepatitis delta virus (HDV) is a satellite RNA virus that depends on hepatitis B virus (HBV) surface proteins (HBsAg) to assemble into infectious virions targeting the same organ (liver) as HBV. Until recently, the evolutionary origin of HDV remained largely unknown. The application of bioinformatics on whole sequence databases lead to discoveries of HDV-like agents (DLA) and shed light on HDV's evolution, expanding our understanding of HDV biology. DLA were identified in heterogeneous groups of vertebrates and invertebrates, highlighting that the evolution of HDV, represented by eight distinct genotypes, is broader and more complex than previously foreseen. In this study, we focused on the characterization of three mammalian DLA discovered in woodchuck (

Indexed as

Hepatitis B virusHepatitis Delta VirusMarmotaVirus ReplicationAnimalsCell DivisionCell LineChiropteraGenotypeHEK293 CellsHepatitis BHepatitis B Surface AntigensHepatitis DHumansRNA, ViralViral Envelope ProteinsHepatitis B Surface AntigensRNA, ViralViral Envelope Proteinscell division-mediated spreadHDVHDV evolutionhepatitis delta virusmammalian delta-like agents

Identifiers

PMID38932152
PMCPMC11209313

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.