ArticleViruses2024
Investigation of Oral Shedding of Torquetenovirus (TTV) in Moderate-to-Severe COVID-19 Hospitalised Patients.
Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Comparative viral load analysis of torque Teno virus and Torque teno mini virus in COVID-19 infected and non-infected individuals in the United Arab Emirates.Molecular biology reports · 2025Article
- TTV Species Diversity as a Novel Biomarker of Immune Dysregulation in Aging.Journal of medical virology · 2025Article
- Torque Teno Virus: Lights and Shades.Viruses · 2025Review
- Review
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
backgroundTorquetenovirus (TTV) is a small DNA virus constituting the human virome. High levels of TTV-DNA have been shown to be associated with immunosuppression and inflammatory chronic disorders.
aimTo assess the possible association between the salivary viral load of TTV-DNA in patients hospitalised due to COVID-19 and disease severity.
methodsSaliva samples collected from 176 patients infected with SARS-CoV-2 were used to investigate the presence of SARS-CoV-2 and TTV-DNA by use of real-time RT-PCR.
resultsThe majority of patients were male with severe COVID-19. Presence of SARS-CoV-2 was observed in the saliva of 64.77% of patients, showing TTV-DNA in 55.68% of them. Patients with impaired clinical conditions (
conclusionsThese results indicate that TTV-DNA in saliva could be a useful biomarker of COVID-19 severity and prognosis.
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Registered trials
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