Evidence map›Paper›PMID 38932122›Full record

ArticleViruses2024

Development of a Fully Protective Pandemic Avian Influenza Subunit Vaccine in Insect Pupae.

Ana Falcón, Susana Martínez-Pulgarín, Sergi López-Serrano, Edel Reytor, Miguel Cid, Maria Del Carmen Nuñez, Lorena Córdoba, Ayub Darji, José M Escribano

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana FalcónAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.
Susana Martínez-PulgarínAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.ORCID 0009-0000-6869-6954
Sergi López-SerranoUnitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Spain.ORCID 0000-0002-0968-7713
Edel ReytorAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.ORCID 0009-0007-3614-1066
Miguel CidAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.
Maria Del Carmen NuñezAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.ORCID 0009-0000-5789-7558
Lorena CórdobaUnitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Spain.
Ayub DarjiUnitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Spain.
José M EscribanoAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.ORCID 0009-0002-0983-9278

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we pioneered an alternative technology for manufacturing subunit influenza hemagglutinin (HA)-based vaccines. This innovative method involves harnessing the pupae of the Lepidoptera

Indexed as

Antibodies, ViralChickensHemagglutinin Glycoproteins, Influenza VirusInfluenza in BirdsInfluenza VaccinesPupaVaccines, SubunitAnimalsBaculoviridaeHumansInfluenza A Virus, H7N1 SubtypeInfluenza A Virus, H7N9 SubtypeMothsPandemicsVaccine DevelopmentAntibodies, ViralHemagglutinin Glycoproteins, Influenza VirusInfluenza VaccinesVaccines, Subunitbaculovirusinsect pupaepandemic influenzasubunit vaccineTrichoplusia ni

Identifiers

PMID38932122
PMCPMC11209067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.