Evidence map›Paper›PMID 38931932›Full record

ReviewPharmaceutics2024

Development of

Anne K Ellis, Thomas B Casale, Michael Kaliner, John Oppenheimer, Jonathan M Spergel, David M Fleischer, David Bernstein, Carlos A Camargo, Richard Lowenthal, Sarina Tanimoto

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Low risk of ocular toxicity following topical ocular administration of epinephrine nasal spray: implications for unintentional exposure.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Neffy: A latest needle-free epinephrine.Saudi journal of anaesthesia
    Review
  13. A Survey of Parental Decision Making in the Selection of Adrenaline Self-Administration Devices.Pediatrics international : official journal of the Japan Pediatric Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anne K EllisDivision of Allergy and Immunology, Department of Medicine, Queen's University, Kingston, ON K7L 3N6, Canada.
Thomas B CasaleMorsani College of Medicine, University of South Florida, Tampa, FL 33602, USA.
Michael KalinerInstitute for Asthma and Allergy, Chevy Chase, MD 20815, USA.
John OppenheimerDepartment of Internal Medicine, University of Medicine and Dentistry of New Jersey-Rutgers New Jersey Medical School, Newark, NJ 07103, USA.ORCID 0009-0002-3260-9630
Jonathan M SpergelDivision of Allergy and Immunology, Children's Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
David M FleischerSection of Allergy and Immunology, Department of Pediatrics, Children's Hospital Colorado, School of Medicine, University of Colorado, Aurora, CO 80045, USA.
David BernsteinBernstein Clinical Research Center, Division of Immunology, Allergy and Rheumatology, College of Medicine, University of Cincinnati, Cincinnati, OH 45236, USA.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-5071-7654
Richard LowenthalARS Pharmaceuticals, Inc., San Diego, CA 92130, USA.
Sarina TanimotoARS Pharmaceuticals, Inc., San Diego, CA 92130, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epinephrine autoinjectors (EAIs) are used for the treatment of severe allergic reactions in a community setting; however, their utility is limited by low prescription fulfillment rates, failure to carry, and failure to use due to fear of needles. Given that delayed administration of epinephrine is associated with increased morbidity/mortality, there has been a growing interest in developing needle-free, easy-to-use delivery devices.

Indexed as

anaphylaxisepinephrinefood allergyintranasal epinephrinenasal sprayout of hospital usepharmacodynamicspharmacokineticssevere allergy

Identifiers

PMID38931932
PMCPMC11207568

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.