Evidence map›Paper›PMID 38931344›Full record

ReviewPharmaceuticals (Basel, Switzerland)2024

Nanoparticle-Mediated Drug Delivery Systems for Precision Targeting in Oncology.

Kamelia Hristova-Panusheva, Charilaos Xenodochidis, Milena Georgieva, Natalia Krasteva

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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  9. Advancing brain immunotherapy through functional nanomaterials.Drug delivery and translational research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kamelia Hristova-PanushevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, "Acad. Georgi Bonchev" Str., Bl. 21, 1113 Sofia, Bulgaria.ORCID 0000-0001-8348-8336
Charilaos XenodochidisInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, "Acad. Georgi Bonchev" Str., Bl. 21, 1113 Sofia, Bulgaria.ORCID 0000-0001-6583-0169
Milena GeorgievaInstitute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, "Acad. Georgi Bonchev" Str., Bl. 21, 1113 Sofia, Bulgaria.ORCID 0000-0002-2371-7544
Natalia KrastevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, "Acad. Georgi Bonchev" Str., Bl. 21, 1113 Sofia, Bulgaria.ORCID 0000-0001-7423-7412

Funding

Bulgarian Science Research Fund KP-06-N59/1/ 2021
6 · The paper itself

Abstract

Nanotechnology has emerged as a transformative force in oncology, facilitating advancements in site-specific cancer therapy and personalized oncomedicine. The development of nanomedicines explicitly targeted to cancer cells represents a pivotal breakthrough, allowing the development of precise interventions. These cancer-cell-targeted nanomedicines operate within the intricate milieu of the tumour microenvironment, further enhancing their therapeutic efficacy. This comprehensive review provides a contemporary perspective on precision cancer medicine and underscores the critical role of nanotechnology in advancing site-specific cancer therapy and personalized oncomedicine. It explores the categorization of nanoparticle types, distinguishing between organic and inorganic variants, and examines their significance in the targeted delivery of anticancer drugs. Current insights into the strategies for developing actively targeted nanomedicines across various cancer types are also provided, thus addressing relevant challenges associated with drug delivery barriers. Promising future directions in personalized cancer nanomedicine approaches are delivered, emphasising the imperative for continued optimization of nanocarriers in precision cancer medicine. The discussion underscores translational research's need to enhance cancer patients' outcomes by refining nanocarrier technologies in nanotechnology-driven, site-specific cancer therapy.

Indexed as

cancer-cell-targeted nanomedicinesnanotechnologypersonalized oncomedicinesite-specific cancer therapytumour microenvironment-targeted nanomedicines

Identifiers

PMID38931344
PMCPMC11206252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.