Evidence map›Paper›PMID 38931240›Full record

ArticleNutrients2024

Time-Dependent Effect of Eggshell Membrane on Monosodium-Iodoacetate-Induced Osteoarthritis: Early-Stage Inflammation Control and Late-Stage Cartilage Protection.

Min Yu, Cheoljin Park, Young Bae Son, So Eun Jo, Seong Hee Jeon, Ye Jin Kim, Sang Bae Han, Jin Tae Hong, Dong Ju Son

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. REJENERAInflammopharmacology · 2026
    Article
  3. Article
  4. Article
  5. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Min YuCollege of Pharmacy, Chungbuk National University, 194-21 Osongsaengmyong 1-ro, Osong-eup, Heungduk-gu, Cheongju 28160, Chungbuk, Republic of Korea.
Cheoljin ParkCollege of Pharmacy, Chungbuk National University, 194-21 Osongsaengmyong 1-ro, Osong-eup, Heungduk-gu, Cheongju 28160, Chungbuk, Republic of Korea.ORCID 0000-0001-9414-0327
Young Bae SonCollege of Pharmacy, Chungbuk National University, 194-21 Osongsaengmyong 1-ro, Osong-eup, Heungduk-gu, Cheongju 28160, Chungbuk, Republic of Korea.
So Eun JoCollege of Pharmacy, Chungbuk National University, 194-21 Osongsaengmyong 1-ro, Osong-eup, Heungduk-gu, Cheongju 28160, Chungbuk, Republic of Korea.
Seong Hee JeonCollege of Pharmacy, Chungbuk National University, 194-21 Osongsaengmyong 1-ro, Osong-eup, Heungduk-gu, Cheongju 28160, Chungbuk, Republic of Korea.
Ye Jin KimCollege of Pharmacy, Chungbuk National University, 194-21 Osongsaengmyong 1-ro, Osong-eup, Heungduk-gu, Cheongju 28160, Chungbuk, Republic of Korea.
Sang Bae HanCollege of Pharmacy, Chungbuk National University, 194-21 Osongsaengmyong 1-ro, Osong-eup, Heungduk-gu, Cheongju 28160, Chungbuk, Republic of Korea.ORCID 0000-0001-6656-6523
Jin Tae HongCollege of Pharmacy, Chungbuk National University, 194-21 Osongsaengmyong 1-ro, Osong-eup, Heungduk-gu, Cheongju 28160, Chungbuk, Republic of Korea.ORCID 0000-0002-6534-9575
Dong Ju SonCollege of Pharmacy, Chungbuk National University, 194-21 Osongsaengmyong 1-ro, Osong-eup, Heungduk-gu, Cheongju 28160, Chungbuk, Republic of Korea.ORCID 0000-0001-7520-6909

Funding

the National Research Foundation of Korea(NRF) funded by the Ministry of Educa-tion(MOE) 2021RIS-001
6 · The paper itself

Abstract

Osteoarthritis (OA) is a chronic degenerative joint disease that causes chronic pain, swelling, stiffness, disability, and significantly reduces the quality of life. Typically, OA is treated using painkillers and non-steroidal anti-inflammatory drugs (NSAIDs). While current pharmacologic treatments are common, their potential side effects have prompted exploration into functional dietary supplements. Recently, eggshell membrane (ESM) has emerged as a potential functional ingredient for joint and connective tissue disorders due to its clinical efficacy in relieving joint pain and stiffness. Despite promising clinical evidence, the effects of ESM on OA progression and its mechanism of action remain poorly understood. This study evaluated the efficacy of Ovomet

Indexed as

Cartilage, ArticularEgg ShellOsteoarthritisAnimalsAnti-Inflammatory AgentsArthralgiaCytokinesDietary SupplementsDisease Models, AnimalInflammationIodoacetic AcidMaleMiceNitric Oxide Synthase Type IIRatsRats, Sprague-DawleyAnti-Inflammatory AgentsCytokinesIodoacetic AcidNitric Oxide Synthase Type IIcartilage-degrading enzymeeggshell membraneinflammationosteoarthritisOvomet

Identifiers

PMID38931240
PMCPMC11206400

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.