Evidence map›Paper›PMID 38931219›Full record

ArticleNutrients2024

Analysis of Alterations in Intestinal Flora in Chinese Elderly with Cardiovascular Disease and Its Association with Trimethylamine.

Yannan He, Song Chen, Yuling Xue, Han Lu, Ziteng Li, Xianxian Jia, Yibing Ning, Qingbin Yuan, Shijie Wang

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yannan HeCollege of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Song ChenCollege of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Yuling XueJunlebao Dairy Group Co., Ltd., Shijiazhuang 050221, China.
Han LuCollege of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.
Ziteng LiCollege of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.ORCID 0009-0001-5386-8909
Xianxian JiaInstitute of Basic Medicine, Hebei Medical University, Shijiazhuang 050017, China.
Yibing NingJunlebao Dairy Group Co., Ltd., Shijiazhuang 050221, China.
Qingbin YuanJunlebao Dairy Group Co., Ltd., Shijiazhuang 050221, China.
Shijie WangCollege of Food and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China.ORCID 0000-0003-2856-5057

Funding

S&T Program of Hebei ;Nature Foundation of Hebei;Science and Technology Research and Development Program of Shijiazhuang;the Industrial Technology Research Institute construction project of Shijiazhuang 22567685H;C2022106012;226790217H;228790859A
6 · The paper itself

Abstract

To investigate the changes in the intestinal flora in the Chinese elderly with cardiovascular disease (CVD) and its correlation with the metabolism of trimethylamine (TMA), the intestinal flora composition of elderly individuals with CVD and healthy elderly individuals was analyzed using 16S rRNA sequencing, the TMA levels in the feces of elderly were detected using headspace-gas chromatography (HS-GC), and four kinds of characterized TMA-producing intestinal bacteria in the elderly were quantified using real-time fluorescence quantitative polymerase chain reaction (qPCR). The results showed that

Indexed as

Cardiovascular DiseasesFecesGastrointestinal MicrobiomeMethylaminesAgedAged, 80 and overBacteriaChinaEast Asian PeopleFemaleHumansMaleMiddle AgedRNA, Ribosomal, 16SMethylaminesRNA, Ribosomal, 16Strimethylamine16S rRNA sequencingcardiovascular disease (CVD)elderlyintestinal bacteriareal-time fluorescence quantitative polymerase chain reaction (qPCR)trimethylamine (TMA)

Identifiers

PMID38931219
PMCPMC11206853

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.