ArticleNutrients2024
Low Prognostic Nutritional Index Predicts In-Hospital Complications and Case Fatality in Patients with Spontaneous Intracerebral Hemorrhage: A Retrospective Study.
Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed.
- Efficacy and safety of SGLT2 inhibitors in elderly patients with type 2 diabetes.Annals of medicine · 2026Article
- Relationship Between Prognostic Nutritional Index and Stroke-Associated Pneumonia in Elderly Patients: A Two-Center Study of Spontaneous Intracerebral Hemorrhage.Food science & nutrition · 2026Article
- Comparative associations of three nutritional indices with hematoma expansion after intracerebral hemorrhage.Frontiers in nutrition · 2026Article
- The impact of early nutritional and immune status assessment on all-cause mortality in patients with intracerebral hemorrhage in the intensive care unit: a retrospective study.Frontiers in medicine · 2026Article
- Serum anion gap and its interaction with diabetes in predicting mortality among critically ill patients with non-traumatic intracerebral hemorrhage.European journal of medical research · 2025Article
- Association of Comorbidity and Inflammatory and Nutritional Markers with Epilepsy and Seizure Frequency.Nutrients · 2025Article
- A nomogram based on systemic inflammation response index and clinical risk factors for prediction of short-term prognosis of very elderly patients with hypertensive intracerebral hemorrhage.Frontiers in medicine · 2025Article
- Relationship between prognostic nutritional index and asthma: a cross-sectional analysis.Frontiers in nutrition · 2025Article
- Malnutrition is associated with severe outcome in elderly patients hospitalised with COVID-19.Scientific reports · 2024Article
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5 authors.
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Abstract
backgroundSpontaneous intracerebral hemorrhage (ICH) is associated with high case fatality and significant healthcare costs. Recent studies emphasize the critical role of nutritional status in affecting outcomes in neurological disorders. This study investigates the relationship between the Prognostic Nutrition Index (PNI) and in-hospital complications and case fatality among patients with ICH.
methodsA retrospective analysis was performed using data from the Changhua Christian Hospital Clinical Research Database between January 2015 and December 2022. Patients under 20 or over 100 years of age or with incomplete medical data were excluded. We utilized restricted cubic spline models, Kaplan-Meier survival analysis, and ROC analysis to assess the association between PNI and clinical outcomes. Propensity score matching analysis was performed to balance these clinical variables between groups.
resultsIn this study, 2402 patients with spontaneous ICH were assessed using the median PNI value of 42.77. The cohort was evenly divided between low and high PNI groups, predominantly male (59.1%), with an average age of 64 years. Patients with lower PNI scores at admission had higher in-hospital complications and increased 28- and 90-day case fatality rates.
conclusionsOur study suggests that PNI could serve as a valuable marker for predicting medical complications and case fatality in patients with spontaneous ICH.
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