Evidence map›Paper›PMID 38931185›Full record

ArticleNutrients2024

Dietary Advanced Glycation End Products (AGEs) and Urinary Fluorescent AGEs in Children and Adolescents: Findings from the Italian I.Family Project.

Marika Dello Russo, Ivana Sirangelo, Fabio Lauria, Annarita Formisano, Clara Iannuzzi, Antje Hebestreit, Valeria Pala, Alfonso Siani, Paola Russo

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. WormCNN-Assisted Establishment and Analysis of Glycation Stress Models inInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marika Dello RussoInstitute of Food Sciences, National Research Council, 83100 Avellino, Italy.ORCID 0000-0002-7630-265X
Ivana SirangeloDepartment of Precision Medicine, University of Campania "L. Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-6408-4990
Fabio LauriaInstitute of Food Sciences, National Research Council, 83100 Avellino, Italy.ORCID 0000-0002-1663-1582
Annarita FormisanoInstitute of Food Sciences, National Research Council, 83100 Avellino, Italy.
Clara IannuzziDepartment of Precision Medicine, University of Campania "L. Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-0092-5997
Antje HebestreitLeibniz Institute for Prevention Research and Epidemiology-BIPS, 28359 Bremen, Germany.ORCID 0000-0001-7354-5958
Valeria PalaEpidemiology and Prevention Unit, Fondazione IRCCS, Istituto Nazionale dei Tumori, 20133 Milan, Italy.ORCID 0000-0001-5438-970X
Alfonso SianiInstitute of Food Sciences, National Research Council, 83100 Avellino, Italy.ORCID 0000-0002-9797-2943
Paola RussoInstitute of Food Sciences, National Research Council, 83100 Avellino, Italy.ORCID 0000-0002-3603-0143

Funding

European Commission 266044
6 · The paper itself

Abstract

Advanced glycation end products (AGEs) have been implicated in chronic diseases in adults, but their role in paediatric populations remains uncertain. This study, conducted on the Italian sample of the I.Family project, aimed to investigate the relationship between dietary and urinary fluorescent AGEs in children and adolescents. The secondary objective was to investigate the sources of dietary AGEs (dAGEs) and their association with dietary composition and anthropometric parameters. Dietary data were collected from 1048 participants via 24 h dietary recall in 2013/2014 to estimate dAGEs intake, while urinary fluorescent AGE levels were measured in 544 individuals. Participants were stratified based on dAGEs intake and compared with respect to urinary fluorescent AGE levels, anthropometric measurements, and dietary intake. The results showed no significant correlation between dietary and urinary fluorescent AGE levels, nor between dAGEs and anthropometric parameters. Notably, higher dAGEs were associated with a diet richer in protein (especially from meat sources) and fat and lower in carbohydrates. In addition, the consumption of ultra-processed foods was lower in participants with a higher DAGE intake. This study highlights the lack of a clear association between dietary and urinary fluorescent AGEs in children, but suggests a distinctive dietary pattern associated with increased dAGEs intake. Further investigation is warranted to elucidate the potential health implications of dAGEs in paediatric populations.

Indexed as

DietGlycation End Products, AdvancedAdolescentAnthropometryChildCross-Sectional StudiesDietary Advanced Glycation End ProductsFemaleHumansItalyMaleDietary Advanced Glycation End ProductsGlycation End Products, Advancedadvanced glycation end products (AGEs)childrendietI.Family projectpopulation studyultra-processed foods (UPF)urinary AGEs

Identifiers

PMID38931185
PMCPMC11206686

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.