ArticleMicromachines2024
Fiber Optic LSPR Sensing AFM1 in Milk with Enhanced Sensitivity by the Hot Spot Effect Based on Nanogap Construction.
Article in Micromachines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Fluorescence resonance energy transfer-based aptasensor for rapid detection of aflatoxin M1 in milk.Mikrochimica acta · 2026Article
- An AuNP-labeled triple-helix molecular switch for ultrasensitive, on-site detection of tetracycline in milk via fiber-optic localized surface plasmon resonance biosensing.Food chemistry: X · 2026Article
- Aflatoxin M1 Determination in Whole Milk with Immersible Silicon Photonic Immunosensor.Toxins · 2025Article
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Authors and funding
7 authors.
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Abstract
The detection of the amount of aflatoxin M1 (AFM1) in milk is crucial for food safety. Here, we utilize a fiber optic (FO) localized surface plasmon resonance (LSPR) biosensor by constructing gold nanoparticle (AuNP) multimers, in which the nanogaps amplified the LSPR signal by the hot spot effect, and achieved a highly sensitive detection of f AFM1. Through the optimization of parameter conditions for the fabrication of the sensor and detection system, a high performance result from the FO LSPR biosensor was obtained, and the method for AFM1 detection was established, with a wide detection range of 0.05-100 ng/mL and a low limit of detection (LOD) of 0.04 ng/mL, and it has been successfully validated with the actual sample milk. Therefore, it is a good strategy to fabricate highly sensitive FO LSPR sensors for detecting AFM1 by constructing AuNP multimers, and this approach is suitable for developing other biosensors.
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