Evidence map›Paper›PMID 38930589›Full record

ArticleMicroorganisms2024

Hepatitis B Virus Prevalence among HIV-Uninfected People Living in Rural and Peri-Urban Areas in Botswana.

Motswedi Anderson, Thabo Mangogola, Bonolo B Phinius, Gorata Mpebe, Christopher O Aimakhu, Wonderful T Choga, Basetsana Phakedi, Lynnette N Bhebhe, Doreen Ditshwanelo, Kabo Baruti and 9 more

Abstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Motswedi AndersonBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.ORCID 0000-0001-9974-9684
Thabo MangogolaBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Bonolo B PhiniusBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.ORCID 0000-0002-0180-2705
Gorata MpebeBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Christopher O AimakhuPan-African University (Life and Earth Sciences Institute), University of Ibadan, Ibadan 200132, Nigeria.
Wonderful T ChogaBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.ORCID 0000-0001-7606-0569
Basetsana PhakediBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Lynnette N BhebheBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.ORCID 0000-0003-0282-0793
Doreen DitshwaneloBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Kabo BarutiBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Linda Mpofu-DoboBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Lebogang OthusitseBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Tsholofelo RatsomaBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Tendani GaolatheBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Joseph MakhemaBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Roger ShapiroBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Shahin LockmanBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.
Sikhulile MoyoBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.ORCID 0000-0003-3821-4592
Simani GaseitsiweBotswana Harvard Health Partnership, Private Bag BO320, Gaborone, Botswana.

Funding

H3ABioNet: a sustainable African Bioinformatics Network for H3AfricaU41HG006941 · NHGRI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA · 2012 to 2017
$14.8M
Training in HIV Genomics, Treatment, and Cure Research in BotswanaD43TW009610 · FIC · THE BOTSWANA HARVARD HEALTH PARTNERSHIP · PI SHAHIN LOCKMAN, Joseph Moeketsi Makhema · 2013 to 2026
$4.4M
Viral Diversity an Innovative Biomarker for Refining Estimates of HIV IncidenceK43TW012350 · FIC · THE BOTSWANA HARVARD HEALTH PARTNERSHIP · PI Sikhulile Moyo · 2022 to 2026
$682k
FIC NIH HHS D43 TW009610FIC NIH HHS K43 TW012350Gates Foundation INV-033558National Institutes of Health (NIH) Common Fund U41HG006941NIH HHS 1G11TW012503-01NIH HHS NIH (award numbers K24 AI131928, K24 AI131924 and K43 TW012350Trials of Excellence in Southern Africa (TESAIII), which is part of the EDCTP2 program support-ed by the European Union CSA2020NoE-3104 TESAIIIWellcome Trust 218770/Z/19/Z)
6 · The paper itself

Abstract

(1) Background: we determined the prevalence of the hepatitis B virus (HBV) amongst people without human immunodeficiency virus (HIV) in rural and peri-urban areas in Botswana. (2) Methods: We screened for the hepatitis B surface antigen (HBsAg) from archived plasma samples of people without HIV (n = 2135) randomly selected from the Botswana Combination Prevention Program (BCPP) (2013-2018). We sequenced 415 bp of the surface region using BigDye sequencing chemistry. (3) Results: The median age of participants was 31 (IQR: 24-46) and 64% (1360/2135) were female. HBV prevalence was 4.0% (86/2135) [95% CI: 3.3-4.9]) and ranged between 0-9.2%. Older participants (>35 years) had increased odds of HBV positivity (OR: 1.94; 95% CI: [1.32-2.86];

Indexed as

AfricagenotypesHBVhepatitis B virusHIV negativemutationsprevalence

Identifiers

PMID38930589
PMCPMC11205512

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.