Evidence map›Paper›PMID 38930429›Full record

ArticleMicroorganisms2024

Development of a Plant-Expressed Subunit Vaccine against Brucellosis.

Daria A Rutkowska, Lissinda H Du Plessis, Essa Suleman, Martha M O'Kennedy, Deepak B Thimiri Govinda Raj, Yolandy Lemmer

Abstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daria A RutkowskaAdvanced Agriculture and Food Cluster, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.ORCID 0000-0001-5120-4255
Lissinda H Du PlessisCentre of Excellence for Pharmaceutical Sciences (PharmacenTM), North-West University, Potchefstroom 2520, South Africa.ORCID 0000-0003-0954-2976
Essa SulemanAdvanced Agriculture and Food Cluster, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.ORCID 0000-0002-2499-7381
Martha M O'KennedyFuture Production and Chemicals Cluster, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.ORCID 0000-0003-3050-7008
Deepak B Thimiri Govinda RajSynthetic Biology and Precision Medicine Centre, Future Production and Chemicals Cluster, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.ORCID 0000-0002-9328-449X
Yolandy LemmerFuture Production and Chemicals Cluster, Council for Scientific and Industrial Research, Pretoria 0001, South Africa.ORCID 0000-0002-6932-3014

Funding

Global Alliance for Livestock Veterinary Medicines Once off prize of $100 000 in the Brucellosis competition
6 · The paper itself

Abstract

Brucellosis is an important bacterial disease of livestock and the most common zoonotic disease. The current vaccines are effective but unsafe, as they result in animal abortions and are pathogenic to humans. Virus-like particles are being investigated as molecular scaffolds for foreign antigen presentation to the immune system. Here, we sought to develop a new-generation vaccine by presenting selected

Indexed as

BrucellaCLPcore-like particleepitopenew generationOrbivirusplant-expressedsubunitvaccine

Identifiers

PMID38930429
PMCPMC11205566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.