Evidence map›Paper›PMID 38930104›Full record

ArticleJournal of clinical medicine2024

Real-Life Evidence of Mepolizumab Treatment in Chronic Rhinosinusitis with Nasal Polyps: A Multicentric Study.

Carlo Cavaliere, Antonella Loperfido, Andrea Ciofalo, Loreta Di Michele, Elona Begvarfaj, Gianluca Bellocchi, Marcella Bugani, Marco de Vincentiis, Antonio Greco, Stefano Millarelli and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Efficacy and safety of mepolizumab in the treatment of CRSwNP in the real-life setting: a review of the literature.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  5. Mepolizumab reduces healthcare resource utilization in patients with chronic rhinosinusitis with nasal polyps: a linked EMR and claims-based pre-post study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  6. Article
  7. Review
  8. Observational
  9. Article
  10. Remission in chronic rhinosinusitis with nasal polyps treated with biologics: a real-life experience.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The Effects of Mepolizumab on CRSwNP: Real-Life Evidence.Journal of personalized medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carlo CavaliereDepartment of Sense Organs, Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-0378-8935
Antonella LoperfidoOtolaryngology Unit, San Camillo Forlanini Hospital, 00152 Rome, Italy.ORCID 0000-0002-7174-8126
Andrea CiofaloDepartment of Sense Organs, Sapienza University, 00185 Rome, Italy.ORCID 0000-0003-1468-459X
Loreta Di MicheleDepartment of Pulmonary Interstitial Diseases, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Elona BegvarfajDepartment of Sense Organs, Sapienza University, 00185 Rome, Italy.
Gianluca BellocchiOtolaryngology Unit, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Marcella BuganiDepartment of Sense Organs, Sapienza University, 00185 Rome, Italy.
Marco de VincentiisDepartment of Sense Organs, Sapienza University, 00185 Rome, Italy.
Antonio GrecoDepartment of Sense Organs, Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-4824-9871
Stefano MillarelliOtolaryngology Unit, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Michaela PlathDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Eleonora SculcoDepartment of Translational and Precision Medicine, Sapienza University, 00185 Rome, Italy.
Simonetta MasieriDepartment of Oral and Maxillofacial Sciences, Sapienza University, 00185 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biologicschronic rhinosinusitis with nasal polypsCRSwNPIL-5mAbMepolizumabmonoclonal antibodies

Identifiers

PMID38930104
PMCPMC11204559

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.