Evidence map›Paper›PMID 38930005›Full record

ReviewJournal of clinical medicine2024

Unraveling the Enigma of Moderate Aortic Stenosis: Challenges and Future Prospects.

Gloria Santangelo, Gabriele Tumminello, Lucia Barbieri, Giulio Pio Federico Mallardi, Andrea Faggiano, Silvia Moscardelli, Andrea Rossi, Fabiana Cozza, Stefano Carugo, Pompilio Faggiano

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gloria SantangeloDepartment of Cardio-Thoracic-Vascular Diseases, Foundation IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Gabriele TumminelloDepartment of Cardio-Thoracic-Vascular Diseases, Foundation IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Lucia BarbieriDepartment of Cardio-Thoracic-Vascular Diseases, Foundation IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Giulio Pio Federico MallardiDepartment of Cardio-Thoracic-Vascular Diseases, Foundation IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0009-0000-2324-871X
Andrea FaggianoDepartment of Cardio-Thoracic-Vascular Diseases, Foundation IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-3247-3203
Silvia MoscardelliDivision of Cardiology, Department of Health Sciences, San Paolo Hospital, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-8389-7575
Andrea RossiOspedale Magalini, 37069 Villafranca, Italy.
Fabiana CozzaCardiothoracic Department Unit, Fondazione Poliambulanza, 25124 Brescia, Italy.
Stefano CarugoDepartment of Cardio-Thoracic-Vascular Diseases, Foundation IRCCS Ca'Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Pompilio FaggianoCardiothoracic Department Unit, Fondazione Poliambulanza, 25124 Brescia, Italy.ORCID 0000-0002-7997-6908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to current guidelines, only clinical surveillance is recommended for patients with moderate aortic valve stenosis (AS), while aortic valve replacement may be considered in patients undergoing surgery for other indications. Recent studies have shown that moderate AS is associated with a high risk of adverse cardiovascular events, including death, especially in patients with left ventricular dysfunction. In this context, multimodality imaging can help to improve the accuracy of moderate AS diagnosis and to assess left ventricular remodeling response. This review discusses the natural history of this valve disease and the role of multimodality imaging in the diagnostic process, summarizes current evidence on the medical and non-medical management, and highlights ongoing trials on valve replacement.

Indexed as

aortic valve replacementdiscordant moderate aortic stenosisiPCSK9left ventricular disfunctionmoderate aortic valve stenosis

Identifiers

PMID38930005
PMCPMC11204855

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.