Evidence map›Paper›PMID 38929747›Full record

ArticleLife (Basel, Switzerland)2024

Acute Kaempferol Stimulation Induces AKT Phosphorylation in HepG2 Cells.

Beatriz Santana-Lima, Lucas Humberto Zimmermann Belaunde, Karine Damaceno de Souza, Matheus Elias Rosa, Jose Eduardo de Carvalho, Joel Machado-Jr, Maria Isabel Cardoso Alonso-Vale, Luciano Caseli, Daniela Gonçales Galasse Rando, Luciana Chagas Caperuto

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Metabolomic Profiling of Taiwanese Roselle (Foods (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Beatriz Santana-LimaPrograma de Pós-Graduação em Biologia Química, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.ORCID 0000-0003-4983-3233
Lucas Humberto Zimmermann BelaundePrograma de Pós-Graduação em Biologia Química, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.
Karine Damaceno de SouzaPrograma de Pós-Graduação em Biologia Química, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.
Matheus Elias RosaPrograma de Pós-Graduação em Química-Ciência e Tecnologia da Sustentabilidade, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.ORCID 0000-0001-5011-9622
Jose Eduardo de CarvalhoDepartamento de Biologia e Ecologia Evolutiva, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.ORCID 0000-0002-7733-3562
Joel Machado-JrDepartamento de Ciências Biológicas, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.ORCID 0000-0001-7907-3314
Maria Isabel Cardoso Alonso-ValePrograma de Pós-Graduação em Biologia Química, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.ORCID 0000-0001-5847-8080
Luciano CaseliPrograma de Pós-Graduação em Química-Ciência e Tecnologia da Sustentabilidade, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.
Daniela Gonçales Galasse RandoPrograma de Pós-Graduação em Biologia Química, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.ORCID 0000-0002-6586-5107
Luciana Chagas CaperutoPrograma de Pós-Graduação em Biologia Química, Instituto de Ciências Ambientais, Químicas e Farmacêuticas-ICAQF, Universidade Federal de São Paulo, Diadema 09913-030, SP, Brazil.ORCID 0000-0002-6008-4010

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo #2009/50041-0, #2019/26686-2, #2022/03736-7, #2019/13618-9
6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) stands as a prevalent global public health issue caused by deficiencies in the action of insulin and/or insulin production. In the liver, insulin plays an important role by inhibiting hepatic glucose production and stimulating glycogen storage, thereby contributing to blood glucose regulation. Kaempferitrin (KP) and kaempferol (KM), flavonoids found in

Indexed as

flavonoidsinsulin signalingliver cellstype 2 diabetes mellitus

Identifiers

PMID38929747
PMCPMC11205056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.