Evidence map›Paper›PMID 38929711›Full record

ArticleLife (Basel, Switzerland)2024

Alpha-Synuclein Gene Alterations Modulate Tyrosine Hydroxylase in Human iPSC-Derived Neurons in a Parkinson's Disease Animal Model.

Luis Daniel Bernal-Conde, Verónica Peña-Martínez, C Alejandra Morato-Torres, Rodrigo Ramos-Acevedo, Óscar Arias-Carrión, Francisco J Padilla-Godínez, Alexa Delgado-González, Marcela Palomero-Rivero, Omar Collazo-Navarrete, Luis O Soto-Rojas and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Luis Daniel Bernal-CondeLaboratory of Regenerative Medicine, Physiology Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Verónica Peña-MartínezLaboratory of Regenerative Medicine, Physiology Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.
C Alejandra Morato-TorresLaboratory of Regenerative Medicine, Physiology Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Rodrigo Ramos-AcevedoLaboratory of Regenerative Medicine, Physiology Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Óscar Arias-CarriónMovement and Sleep Disorders Unit, Dr. Manuel Gea González General Hospital, Mexico City 14080, Mexico.ORCID 0000-0002-9982-7571
Francisco J Padilla-GodínezLaboratory of Regenerative Medicine, Physiology Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Alexa Delgado-GonzálezLaboratory of Regenerative Medicine, Physiology Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Marcela Palomero-RiveroNeurodevelopment and Physiology Department, Neuroscience Division, Institute of Cell Physiology, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Omar Collazo-NavarreteNational Laboratory of Genomic Resources, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Luis O Soto-RojasLaboratory of Molecular Pathogenesis, Laboratory 4, Building A4, Medical Surgeon Career, Faculty of Higher Studies Iztacala, National Autonomous University of Mexico, Mexico City 54090, Mexico.ORCID 0000-0002-5013-3608
Margarita Gómez-ChavarínLaboratory of Regenerative Medicine, Physiology Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Birgitt SchüleDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA.ORCID 0000-0002-9952-5776
Magdalena Guerra-CrespoLaboratory of Regenerative Medicine, Physiology Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.

Funding

CONAHCyT 1037918CONAHCyT 484013CONAHCyT A1-S-10064DGAPA-PAPIIT IA205423DGAPA-PAPIIT IN219623
6 · The paper itself

Abstract

Parkinson's disease (PD) caused by

Indexed as

6-OHDAalpha-synucleincell transplantdopaminergic neuronshuman induced pluripotent stem cellsParkinson’s disease

Identifiers

PMID38929711
PMCPMC11204703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.