Evidence map›Paper›PMID 38929686›Full record

ArticleLife (Basel, Switzerland)2024

30-Second Chair Stand and 5-Times Sit-to-Stand Tests Are Interesting Tools for Assessing Disability and Ability to Ambulate among Patients with Multiple Sclerosis.

Andrea Polidori, Mattia Malagoli, Rosario Giacalone, Giampaolo Brichetto, Margherita Monti Bragadin, Valeria Prada

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Rotational Power: A New Accelerometer-Derived Metric to Assess Functional Impairment in Multiple Sclerosis.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea PolidoriScientific Research Area, Fondazione Italiana Sclerosi Multipla (FISM), 16149 Genova, Italy.ORCID 0009-0003-7429-3061
Mattia MalagoliServizio Riabilitazione Liguria, Associazione Italiana Sclerosi Multipla (AISM), 16149 Genova, Italy.ORCID 0009-0001-0546-5304
Rosario GiacaloneScientific Research Area, Fondazione Italiana Sclerosi Multipla (FISM), 16149 Genova, Italy.ORCID 0009-0003-8916-844X
Giampaolo BrichettoScientific Research Area, Fondazione Italiana Sclerosi Multipla (FISM), 16149 Genova, Italy.ORCID 0000-0003-2026-3572
Margherita Monti BragadinScientific Research Area, Fondazione Italiana Sclerosi Multipla (FISM), 16149 Genova, Italy.
Valeria PradaScientific Research Area, Fondazione Italiana Sclerosi Multipla (FISM), 16149 Genova, Italy.ORCID 0000-0001-5756-0576

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple Sclerosis (MS) is a demyelinating and chronic disease with variable neurological symptoms. There are different scales that score the level of disability, but only few papers have taken into consideration the 5-times sit-to-stand (5STS) test and the 30 s chair stand test (30CST), which are valid and easily obtainable indicators of other neurological diseases. The aim of our research is to verify the validity, reproducibility, and responsiveness of these tests. Patients afflicted with MS were enrolled in the AISM outpatient facility. The inclusion criterion was an EDSS score less than 6.5. We performed the 5STS, 30CST, and timed 25-foot walk (T25-FW) tests and recorded EDSS scores in the first evaluation. Then, we recorded the performance after 5 days (conducted by a second blind operator to ensure test-retest reproducibility), and the last evaluation was made after 12 sessions of physiotherapy. We recruited 38 patients diagnosed with MS. The results show significant data regarding validity, reproducibility, and responsiveness for both scales. The data argue in favor of adding these tests to the relevant clinical assessments. These two tests are simple, reliable, and easy to administer, and the data confirm that they can be included in the evaluation of patients with MS.

Indexed as

multiple sclerosisoutcome assessmentoutcome measuresrehabilitationtreatment outcome

Identifiers

PMID38929686
PMCPMC11205157

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.