Evidence map›Paper›PMID 38929485›Full record

ReviewMedicina (Kaunas, Lithuania)2024

Currently Available Treatment Modalities for Uterine Fibroids.

Jelena Micić, Maja Macura, Mladen Andjić, Katarina Ivanović, Jelena Dotlić, Dušan D Micić, Vladimir Arsenijević, Jelena Stojnić, Jovan Bila, Sandra Babić and 3 more

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Model Based on Ultrasound Radiomics and Machine Learning for Differentiating Uterine Fibroids and Adenomyomas.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  3. Contemporary Management of Uterine Fibroids.Journal of clinical medicine · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Pharmacological activities ofFrontiers in pharmacology · 2026
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jelena MicićClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0001-5686-0307
Maja MacuraClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Mladen AndjićClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Katarina IvanovićClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0001-9176-9736
Jelena DotlićClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Dušan D MicićFaculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Vladimir ArsenijevićFaculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Jelena StojnićClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0003-0359-9568
Jovan BilaClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Sandra BabićClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-7812-9002
Una ŠljivančaninClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Danka Mostić StanišićClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Milan DokićClinic of Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-1528-7732

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine fibroids (leiomyomas and myomas) are the most common benign gynecological condition in patients presenting with abnormal uterine bleeding, pelvic masses causing pressure or pain, infertility and obstetric complications. Almost a third of women with fibroids need treatment due to symptoms.

objectivesIn this review we present all currently available treatment modalities for uterine fibroids.

methodsAn extensive search for the available data regarding surgical, medical and other treatment options for uterine fibroids was conducted. REVIEW: Nowadays, treatment for fibroids is intended to control symptoms while preserving future fertility. The choice of treatment depends on the patient's age and fertility and the number, size and location of the fibroids. Current management strategies mainly involve surgical interventions (hysterectomy and myomectomy hysteroscopy, laparoscopy or laparotomy). Other surgical and non-surgical minimally invasive techniques include interventions performed under radiologic or ultrasound guidance (uterine artery embolization and occlusion, myolysis, magnetic resonance-guided focused ultrasound surgery, radiofrequency ablation of fibroids and endometrial ablation). Medical treatment options for fibroids are still restricted and available medications (progestogens, combined oral contraceptives andgonadotropin-releasing hormone agonists and antagonists) are generally used for short-term treatment of fibroid-induced bleeding. Recently, it was shown that SPRMs could be administered intermittently long-term with good results on bleeding and fibroid size reduction. Novel medical treatments are still under investigation but with promising results.

conclusionsTreatment of fibroids must be individualized based on the presence and severity of symptoms and the patient's desire for definitive treatment or fertility preservation.

Indexed as

LeiomyomaFemaleHumansHysterectomyUterine Artery EmbolizationUterine MyomectomyUterine Neoplasmsmanagementmedicamentsminimally invasive proceduresmyomasurgery

Identifiers

PMID38929485
PMCPMC11205795

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.