Development and Validation of a Simple and Reliable HPLC-UV Method for Determining Gemcitabine Levels: Application in Pharmacokinetic Analysis.

Konstantinos Lafazanis, Elias Begas, Irida Papapostolou, Hermis Iatrou, Nikos Sakellaridis, Dimitrios Vlassopoulos, Konstantinos Dimas

Abstract read

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In one paragraph

Article in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Clinical application and drug resistance mechanism of gemcitabine.Frontiers in cell and developmental biology · 2025
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantinos LafazanisDepartment of Pharmacology, Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece.

Elias BegasDepartment of Pharmacology, Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece.

Irida PapapostolouDepartment of Pharmacology, Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece.ORCID 0000-0002-7058-5257

Hermis IatrouIndustrial Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, 10676 Athens, Greece.ORCID 0000-0001-9358-0769

Nikos SakellaridisDepartment of Pharmacology, Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece.

Dimitrios VlassopoulosFORTH, Institute for Electronic Structure and Laser, 71110 Heraklion, Greece.ORCID 0000-0003-0866-1930

Konstantinos DimasDepartment of Pharmacology, Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece.

Funding

General Secretariat for Research and Technology T1EDK-01612

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DeoxycytidineGemcitabineAnimalsAntimetabolites, AntineoplasticChromatography, High Pressure LiquidMiceMice, Inbred NODMice, SCIDReproducibility of ResultsAntimetabolites, AntineoplasticDeoxycytidineGemcitabinegemcitabineHPLC-UVpharmacokinetic analysis

Identifiers

PMID38929481

DOI10.3390/medicina60060864

PMCPMC11205493

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.