Evidence map›Paper›PMID 38929056›Full record

ArticleInternational journal of environmental research and public health2024

Sensitivity of Mouse Lung Nuclear Receptors to Electronic Cigarette Aerosols and Influence of Sex Differences: A Pilot Study.

Shikha Sharma, Dustin Rousselle, Erik Parker, Carolyn Damilola Ekpruke, Rachel Alford, Maksat Babayev, Sarah Commodore, Patricia Silveyra

Abstract read
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In one paragraph

Article in International journal of environmental research and public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shikha SharmaDepartment of Environmental and Occupational Health, School of Public Health, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0001-5948-292X
Dustin RousselleDepartment of Environmental and Occupational Health, School of Public Health, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0003-3377-9324
Erik ParkerBiostatistics Consulting Center, Department of Epidemiology and Biostatistics, School of Public Health, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0002-5537-7900
Carolyn Damilola EkprukeDepartment of Environmental and Occupational Health, School of Public Health, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0002-9045-4457
Rachel AlfordDepartment of Environmental and Occupational Health, School of Public Health, Indiana University, Bloomington, IN 47405, USA.
Maksat BabayevDepartment of Environmental and Occupational Health, School of Public Health, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0002-2110-4218
Sarah CommodoreDepartment of Environmental and Occupational Health, School of Public Health, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0002-9070-0654
Patricia SilveyraDepartment of Environmental and Occupational Health, School of Public Health, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0001-7083-8915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emerging concern about chemicals in electronic cigarettes, even those without nicotine, demands the development of advanced criteria for their exposure and risk assessment. This study aims to highlight the sensitivity of lung nuclear receptors (NRs) to electronic cigarette e-liquids, independent of nicotine presence, and the influence of the sex variable on these effects. Adult male and female C57BL/6J mice were exposed to electronic cigarettes with 0%, 3%, and 6% nicotine daily (70 mL, 3.3 s, 1 puff per min/30 min) for 14 days, using the inExpose full body chamber (SCIREQ). Following exposure, lung tissues were harvested, and RNA extracted. The expression of 84 NRs was determined using the RT

Indexed as

AerosolsElectronic Nicotine Delivery SystemsLungMice, Inbred C57BLNicotineReceptors, Cytoplasmic and NuclearAnimalsFemaleMaleMicePilot ProjectsSex FactorsAerosolsNicotineReceptors, Cytoplasmic and Nuclearchemicals of concern in ENDS (Electronic Nicotine Delivery Systems)electronic cigaretteE-liquidslungsnicotinenuclear receptorssex differences

Identifiers

PMID38929056
PMCPMC11203813

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.