Evidence map›Paper›PMID 38929022›Full record

Trial reportInternational journal of environmental research and public health2024

Childhood Adversities and the ATTACH

Zhiyuan Yu, Steve Cole, Kharah Ross, Martha Hart, Lubna Anis, Nicole Letourneau

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhiyuan YuSchool of Nursing, Johns Hopkins University, 525 N Wolfe St., Baltimore, MD 21205, USA.
Steve ColeSchool of Medicine, University of California-Los Angeles, Le Conte Ave, Los Angeles, CA 10833, USA.
Kharah RossDepartment of Psychology, Athabasca University, 1 University Dr., Athabasca, AB T9S 3A3, Canada.ORCID 0000-0002-1472-5630
Martha HartAlberta Children's Hospital Research Institute, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada.
Lubna AnisAlberta Children's Hospital Research Institute, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada.
Nicole LetourneauFaculty of Nursing & Cumming School of Medicine, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-7468-915X

Funding

An anonymous donor NAHarvard Center on the Developing Child Frontiers in Innovation program. NA
6 · The paper itself

Abstract

objectiveTo determine whether maternal Adverse Childhood Experiences (ACEs) are (a) associated with increased inflammatory gene expression in mother-child dyads and (b) whether a parenting intervention (ATTACH™) moderates the association between maternal ACEs and mother and/or child inflammatory gene expression.

methodsTwenty mother-child dyads, recruited from a domestic violence shelter in Calgary, AB, Canada, were randomized into an ATTACH™ parenting intervention group (

resultsHigher maternal ACEs were associated with higher child CTRA scores (

conclusionsMaternal ACEs could exert an intergenerational impact on child inflammatory activity, and this association could be moderated by participating in the ATTACH™ parenting intervention.

Indexed as

Adverse Childhood ExperiencesAdultChildChild, PreschoolFemaleGene ExpressionHumansInflammationMaleMothersParentingadverse childhood experiencesATTACH™CTRAimmune cell gene expressionparenting intervention

Identifiers

PMID38929022
PMCPMC11204101

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.