Evidence map›Paper›PMID 38928929›Full record

ReviewInternational journal of environmental research and public health2024

Synthetic Colors in Food: A Warning for Children's Health.

Zandleme Birino de Oliveira, Darlene Vitória Silva da Costa, Ana Caroline da Silva Dos Santos, Antônio Quaresma da Silva Júnior, Amanda de Lima Silva, Raphael Carlos Ferrer de Santana, Isabella Cristhina Gonçalves Costa, Sara Freitas de Sousa Ramos, Gabriel Padilla, Silvia Katrine Rabelo da Silva

Abstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  15. Article
  16. Food as Medicine for Hypertension: Microbiota as Mediators.Hypertension (Dallas, Tex. : 1979) · 2025
    Review
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zandleme Birino de OliveiraPrograma de Pós-Graduação em Recursos Naturais da Amazônia, Universidade Federal do Oeste do Pará, Santarém 68040-255, PA, Brazil.
Darlene Vitória Silva da CostaLaboratório de Microbiologia, Instituto de Saúde Coletiva, Universidade Federal do Oeste do Pará, Santarém 68040-255, PA, Brazil.
Ana Caroline da Silva Dos SantosLaboratório de Microbiologia, Instituto de Saúde Coletiva, Universidade Federal do Oeste do Pará, Santarém 68040-255, PA, Brazil.
Antônio Quaresma da Silva JúniorPrograma de Pós-Graduação em Biodiversidade e Biotecnologia da Rede Bionorte, Universidade Federal do Oeste do Pará, Santarém 68040-255, PA, Brazil.
Amanda de Lima SilvaLaboratório de Microbiologia, Instituto de Saúde Coletiva, Universidade Federal do Oeste do Pará, Santarém 68040-255, PA, Brazil.ORCID 0000-0003-4414-202X
Raphael Carlos Ferrer de SantanaLaboratório de Microbiologia, Instituto de Saúde Coletiva, Universidade Federal do Oeste do Pará, Santarém 68040-255, PA, Brazil.
Isabella Cristhina Gonçalves CostaLaboratório de Microbiologia, Instituto de Saúde Coletiva, Universidade Federal do Oeste do Pará, Santarém 68040-255, PA, Brazil.
Sara Freitas de Sousa RamosLaboratório de Microbiologia, Instituto de Saúde Coletiva, Universidade Federal do Oeste do Pará, Santarém 68040-255, PA, Brazil.
Gabriel PadillaDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil.
Silvia Katrine Rabelo da SilvaPrograma de Pós-Graduação em Recursos Naturais da Amazônia, Universidade Federal do Oeste do Pará, Santarém 68040-255, PA, Brazil.ORCID 0000-0002-9408-131X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study addressed the harmful effects of artificial colors in pediatric populations, including children diagnosed with Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD), as well as those without behavioral disorders. There is a consensus that synthetic food colorings have several impacts on consumers, especially pediatrics, due to their influence on sensory appeal, which can encourage preference for certain foods. The results revealed that these color additives are directly linked to a series of health problems, with a greater impact on children, including a predisposition to pathological conditions such as carcinogenic, allergenic, mutagenic, cytotoxic, and clastogenic activities, as well as gastrointestinal and respiratory problems, in addition to behavioral changes in children with and without diagnosed disorders. The harms of synthetic dyes in children with or without comorbidities are worrying and require a careful and proactive approach from parents, caregivers and public authorities.

Indexed as

Child HealthFood Coloring AgentsAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildChild, PreschoolHumansFood Coloring Agentsbehavioral disordersfood additivessynthetic dyestoxicity

Identifiers

PMID38928929
PMCPMC11203549

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.