Evidence map›Paper›PMID 38928868›Full record

ArticleFoods (Basel, Switzerland)2024

Investigating the Impact of Pineapple-Whey Protein Fermentation Products on Cefixime-Induced Intestinal Flora Dysbiosis in Mice Using 16S Sequencing and Untargeted Metabolomics Techniques.

Jiawei Luo, Shan Xiao, Da Ma, Junhan Xiang, Bo Wang, Yanxue Cai, Jihui Wang

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Effects of inoculation withFood chemistry: X · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiawei LuoSchool of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.
Shan XiaoSchool of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.
Da MaSchool of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.
Junhan XiangSchool of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.
Bo WangSchool of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.
Yanxue CaiSchool of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.
Jihui WangSchool of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.

Funding

Dongguan Institute of Science and Technology High Level Talent Research Start Project GC300501-139
6 · The paper itself

Abstract

In our previous study, a new fermented food (PWF) created by utilizing pineapple by-products and whey proteins as a matrix via co-fermentation with lactic acid bacteria and yeast was developed, and, in the current study, we examined the impact of a pineapple-whey protein fermentation product on a cefixime-induced dysbiosis model in mice using 16S sequencing and untargeted metabolomics techniques. The results indicated that the pineapple-whey protein fermentation product played a positive role in restoring the intestinal flora. In this study, cefixime reduced the overall abundance of intestinal flora and decreased the relative abundance of probiotics in the gut, while also inhibiting amino acid metabolism. The addition of PWF normalized the intestinal flora to a steady state, significantly increasing the populations of

Indexed as

cefiximeintestinal microbiotametabolomepineapple–whey protein fermentation product

Identifiers

PMID38928868
PMCPMC11202880

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.