Evidence map›Paper›PMID 38928857›Full record

ArticleFoods (Basel, Switzerland)2024

Prunin Laurate Derived from Natural Substances Shows Antibacterial Activity against the Periodontal Pathogen

Erika Wada, Chiharu Ito, Mai Shinohara, Satoshi Handa, Miki Maetani, Mayo Yasugi, Masami Miyake, Tatsuji Sakamoto, Ayaka Yazawa, Shigeki Kamitani

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Discovery of Gingipains andFoods (Basel, Switzerland) · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Erika WadaNutrition Support Course, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Habikino 583-8555, Osaka, Japan.
Chiharu ItoDivision of Clinical Nutrition, School of Comprehensive Rehabilitation, Osaka Prefecture University, Habikino 583-8555, Osaka, Japan.
Mai ShinoharaNutrition Support Course, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Habikino 583-8555, Osaka, Japan.
Satoshi HandaGraduate School of Agriculture, Osaka Metropolitan University, Sakai 599-8531, Osaka, Japan.
Miki MaetaniDivision of Clinical Nutrition, School of Comprehensive Rehabilitation, Osaka Prefecture University, Habikino 583-8555, Osaka, Japan.
Mayo YasugiGraduate School of Veterinary Science, Osaka Metropolitan University, Izumisano 598-8531, Osaka, Japan.ORCID 0000-0002-9688-2006
Masami MiyakeGraduate School of Veterinary Science, Osaka Metropolitan University, Izumisano 598-8531, Osaka, Japan.
Tatsuji SakamotoGraduate School of Agriculture, Osaka Metropolitan University, Sakai 599-8531, Osaka, Japan.
Ayaka YazawaNutrition Support Course, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Habikino 583-8555, Osaka, Japan.ORCID 0000-0002-8686-3880
Shigeki KamitaniNutrition Support Course, Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Habikino 583-8555, Osaka, Japan.ORCID 0000-0002-1268-4652

Funding

Japan Society for the Promotion of Science KAKENHI 17K00867.
6 · The paper itself

Abstract

Periodontal disease is an inflammatory disease caused by infection with periodontopathogenic bacteria. Oral care is essential to prevent and control periodontal disease, which affects oral and systemic health. However, many oral hygiene products currently on the market were developed as disinfectants, and their intense irritation makes their use difficult for young children and older people. This study investigated the antibacterial effects of prunin laurate (Pru-C12) and its analogs on periodontopathogenic bacteria,

Indexed as

antibacterial activityflavanoneperiodontal diseasePorphyromonas gingivalis

Identifiers

PMID38928857
PMCPMC11202431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.