Evidence map›Paper›PMID 38928697›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Introducing a Novel Innovative Technique for the Recording and Interpretation of Dynamic Coronary Angiography.

Thach Nguyen, Khiem Ngo, Tri Loc Vu, Hien Q Nguyen, Dat H Pham, Mihas Kodenchery, Marco Zuin, Gianluca Rigatelli, Aravinda Nanjundappa, Michael Gibson

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thach NguyenCardiovascular Research Laboratories, Methodist Hospital, Merrillville, IN 46410, USA.ORCID 0000-0002-1252-8174
Khiem NgoDepartment of Medicine, University of Texas Rio Grande Valley, Valley Baptist Medical Center, Harlingen, TX 78550, USA.
Tri Loc VuCardiovascular Research Laboratories, Methodist Hospital, Merrillville, IN 46410, USA.ORCID 0000-0002-4448-9421
Hien Q NguyenCardiovascular Research Laboratories, Methodist Hospital, Merrillville, IN 46410, USA.
Dat H PhamDepartment of Medicine, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA.
Mihas KodencheryCardiovascular Research Laboratories, Methodist Hospital, Merrillville, IN 46410, USA.
Marco ZuinDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-4559-1292
Gianluca RigatelliInterventional Cardiology Unit, Division of Cardiology, AULSS6 Ospedali Riuniti Padova Sud, 35043 Padova, Italy.ORCID 0000-0003-0920-5021
Aravinda NanjundappaPeripheral Interventions, Cardiovascular Department, Cleveland Clinics Main Campus, Cleveland, OH 44195, USA.
Michael GibsonBaim Institute of Clinical Research, Harvard Medical School, Boston, MA 02115, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the study of coronary artery disease (CAD), the mechanism of plaque formation and development is still an important subject for investigation. A limitation of current coronary angiography (CAG) is that it can only show static images of the narrowing of arterial channels without identifying the mechanism of the disease or predicting its progression or regression. To address this limitation, the CAG technique has been modified. The new approach emphasizes identifying and analyzing blood flow patterns, employing methodologies akin to those used by hydraulic engineers for fluid or gas movement through domestic or industrial pipes and pumps. With the new technique, various flow patterns and arterial phenomena-such as laminar, turbulent, antegrade, retrograde, and recirculating flow and potentially water hammer shock and vortex formation-are identified, recorded, and classified. These phenomena are then correlated with the presence of lesions at different locations within the coronary vasculature. The formation and growth of these lesions are explained from the perspective of fluid mechanics. As the pathophysiology of CAD and other cardiovascular conditions becomes clearer, new medical, surgical, and interventional treatments could be developed to reverse abnormal coronary flow dynamics and restore laminar flow, leading to improved clinical outcomes.

Indexed as

antegrade coronary flowcoronary collisiondynamic coronary angiographylaminar flowre-circulating flowretrograde coronary flowturbulent flowwater hammer shock

Identifiers

PMID38928697
PMCPMC11203051

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.