Evidence map›Paper›PMID 38928678›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Deep Learning-Based Prediction Model for the Cobb Angle in Adolescent Idiopathic Scoliosis Patients.

Chun-Sing Elvis Chui, Zhong He, Tsz-Ping Lam, Ka-Kwan Kyle Mak, Hin-Ting Randy Ng, Chun-Hai Ericsson Fung, Mei-Shuen Chan, Sheung-Wai Law, Yuk-Wai Wayne Lee, Lik-Hang Alec Hung and 10 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Prediction of Cobb angle progression in female patients with mild-to-moderate adolescent idiopathic scoliosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  6. Machine learning-based prediction of pediatric scoliosis using foot pressure and body angles.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Chun-Sing Elvis ChuiDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
Zhong HeDivision of Spine Surgery, Department of Orthopedic Surgery, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210000, China.
Tsz-Ping LamDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-2427-2719
Ka-Kwan Kyle MakDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
Hin-Ting Randy NgDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
Chun-Hai Ericsson FungDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
Mei-Shuen ChanDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
Sheung-Wai LawDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
Yuk-Wai Wayne LeeDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-0486-360X
Lik-Hang Alec HungDepartment of Orthopaedics and Traumatology, Prince of Wales Hospital, Hong Kong, China.
Chiu-Wing Winnie ChuDepartment of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0003-4962-4132
Sze-Yi Sibyl MakDepartment of Mechanical Engineering, The University of Hong Kong, Hong Kong, China.
Wing-Fung Edmond YauKoln 3D Technology (Medical) Limited Company, Hong Kong, China.
Zhen LiuDivision of Spine Surgery, Department of Orthopedic Surgery, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210000, China.
Wu-Jun LiNational Institute of Healthcare Data Science, Nanjing University, Nanjing 210023, China.
Zezhang ZhuDivision of Spine Surgery, Department of Orthopedic Surgery, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210000, China.
Man Yeung Ronald WongDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
Chun-Yiu Jack ChengDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0001-8153-364X
Yong QiuDivision of Spine Surgery, Department of Orthopedic Surgery, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210000, China.
Shu-Hang Patrick YungDepartment of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.

Funding

China Postdoctoral Science Foundation 2022M711581Innovation and Technology Commission GHP/100/21SZInnovation and Technology Commission GHP/180/20SZInnovation and Technology Commission ITSP Tier3 (ITS/172/16))Innovation and Technology Commission PRP/027/20FXJiangsu provincial key research and development program BE2023658Nanjing Medical Science and technology development Foundation YKK22098National Key Research and Development Program of China 2023YFC2507700Natural Science Foundation of Jiangsu Province BK20230147
6 · The paper itself

Abstract

Scoliosis, characterized by spine deformity, is most common in adolescent idiopathic scoliosis (AIS). Manual Cobb angle measurement limitations underscore the need for automated tools. This study employed a vertebral landmark extraction method and Feedforward Neural Network (FNN) to predict scoliosis progression in 79 AIS patients. The novel intervertebral angles matrix format showcased results. The mean absolute error for the intervertebral angle progression was 1.5 degrees, while the Pearson correlation of the predicted Cobb angles was 0.86. The accuracy in classifying Cobb angles (<15°, 15-25°, 25-35°, 35-45°, >45°) was 0.85, with 0.65 sensitivity and 0.91 specificity. The FNN demonstrated superior accuracy, sensitivity, and specificity, aiding in tailored treatments for potential scoliosis progression. Addressing FNNs' over-fitting issue through strategies like "dropout" or regularization could further enhance their performance. This study presents a promising step towards automated scoliosis diagnosis and prognosis.

Indexed as

adolescent idiopathic scoliosis (AIS)Cobb anglesFeedforward Neural Network (FNN)

Identifiers

PMID38928678
PMCPMC11203267

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.