Evidence map›Paper›PMID 38928625›Full record

ArticleDiagnostics (Basel, Switzerland)2024

A Novel Noninvasive Screening Tool for Dry Eye Disease.

Sabrina Vaccaro, Massimiliano Borselli, Giovanni Scalia, Costanza Rossi, Mario Damiano Toro, Robert Rejdak, Marco Pellegrini, Vincenzo Scorcia, Giuseppe Giannaccare

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Unveiling dry eye disease prior to cataract surgery: A multicenter clinical study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sabrina VaccaroDepartment of Ophthalmology, University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.
Massimiliano BorselliDepartment of Ophthalmology, University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0001-5262-9765
Giovanni ScaliaDepartment of Ophthalmology, University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0001-9115-5101
Costanza RossiDepartment of Ophthalmology, University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.
Mario Damiano ToroEye Clinic, Public Health Department, University of Naples Federico II, Via S. Pansini 5, 80133 Naples, Italy.ORCID 0000-0001-7152-2613
Robert RejdakDepartment of General and Pediatric Ophthalmology, Medical University of Lublin, 20-079 Lublin, Poland.
Marco PellegriniDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-6419-6941
Vincenzo ScorciaDepartment of Ophthalmology, University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0001-6826-7957
Giuseppe GiannaccareEye Clinic, Department of Surgical Sciences, University of Cagliari, Via Università 40, 09124 Cagliari, Italy.ORCID 0000-0003-2617-0289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the feasibility and the diagnostic accuracy of the new tool, DEvice© (AI, Rome, Italy), for screening patients with dry eye disease (DED).

methodsThis study was performed at the University Magna Græcia of Catanzaro. Enrolled patients were classified as affected by DED (group 1) or not (group 2) using an already validated tool (Keratograph 5M, Oculus, Germany), evaluating the noninvasive keratograph breakup time (NIKBUT), tear meniscus height (TMH), meibomian gland loss (MGL), and bulbar redness. All the patients were then examined by means of DEvice©, which allowed the measurement of the relative humidity (RH) and temperature of the ocular surface. Symptoms were scored using the Ocular Surface Disease Index (OSDI) questionnaire.

resultsOverall, 40 patients (17 males and 23 females, mean age 38.0 ± 17.1 years) were included: of these, 20 belonged to group 1 and the remaining 20 to group 2. Using Keratograph 5M, significant differences between groups 1 and 2 were detected for NIKBUT-first (respectively, 4.97 ± 1.85 vs. 13.95 ± 4.8 s;

conclusionsThe DEvice© can effectively discriminate DED patients from healthy subjects. The parameter RH showed good sensitivity, making this tool ideal for a fast and noninvasive DED screening.

Indexed as

devicediagnosisdry eyenoninvasive diagnosisscreening

Identifiers

PMID38928625
PMCPMC11202972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.