Evidence map›Paper›PMID 38928515›Full record

ArticleInternational journal of molecular sciences2024

Evaluation of Microvascular Density in Glioblastomas in Relation to p53 and Ki67 Immunoexpression.

Tamás-Csaba Sipos, Attila Kövecsi, Lóránd Kocsis, Monica Nagy-Bota, Zsuzsánna Pap

Abstract read
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Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tamás-Csaba SiposDepartment of Anatomy and Embryology, "George Emil Palade" University of Medicine, Pharmacy, Sciences and Technology of Târgu Mures, 540142 Târgu Mures, Romania.ORCID 0009-0003-2249-3918
Attila KövecsiPathology Department, County Emergency Clinical Hospital of Târgu Mureș, 540136 Târgu Mureș, Romania.ORCID 0000-0002-2529-2818
Lóránd KocsisDepartment of Anatomy and Embryology, "George Emil Palade" University of Medicine, Pharmacy, Sciences and Technology of Târgu Mures, 540142 Târgu Mures, Romania.ORCID 0000-0001-8875-0874
Monica Nagy-BotaDepartment of Anatomy and Embryology, "George Emil Palade" University of Medicine, Pharmacy, Sciences and Technology of Târgu Mures, 540142 Târgu Mures, Romania.
Zsuzsánna PapDepartment of Anatomy and Embryology, "George Emil Palade" University of Medicine, Pharmacy, Sciences and Technology of Târgu Mures, 540142 Târgu Mures, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma is the most aggressive tumor in the central nervous system, with a survival rate of less than 15 months despite multimodal therapy. Tumor recurrence frequently occurs after removal. Tumoral angiogenesis, the formation of neovessels, has a positive impact on tumor progression and invasion, although there are controversial results in the specialized literature regarding its impact on survival. This study aims to correlate the immunoexpression of angiogenesis markers (CD34, CD105) with the proliferation index Ki67 and

Indexed as

Brain NeoplasmsGlioblastomaKi-67 AntigenMicrovascular DensityTumor Suppressor Protein p53AdultAgedAntigens, CD34Biomarkers, TumorEndoglinFemaleHumansImmunohistochemistryIsocitrate DehydrogenaseMaleMiddle AgedAntigens, CD34ATRX protein, humanBiomarkers, TumorEndoglinENG protein, humanIDH1 protein, humanIsocitrate DehydrogenaseKi-67 AntigenMKI67 protein, humanTP53 protein, humanTumor Suppressor Protein p53X-linked Nuclear ProteinangiogenesisCD105CD34glioblastomaIDH1Ki67p53

Identifiers

PMID38928515
PMCPMC11204252

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.