ArticleInternational journal of molecular sciences2024
Upscaling and Risk Evaluation of the Synthesis of the 3,5-Diamino-1H-Pyrazole, Disperazol.
Charlotte Uldahl Jansen, Katja Egeskov Grier, Jens Bo Andersen, Louise Dahl Hultqvist, Martin Nilsson, Claus Moser, Michael Graz, Tim Tolker-Nielsen, Michael Givskov, Katrine Qvortrup
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Charlotte Uldahl JansenDepartment of Chemistry, Technical University of Denmark, DK-2800 Lyngby, Denmark.ORCID 0000-0002-1168-8002 Katja Egeskov GrierDepartment of Chemistry, Technical University of Denmark, DK-2800 Lyngby, Denmark.ORCID 0000-0002-9854-1440 Jens Bo AndersenCosterton Biofilm Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.ORCID 0000-0003-1720-1581 Louise Dahl HultqvistCosterton Biofilm Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.ORCID 0000-0003-0256-892X Claus MoserCosterton Biofilm Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Michael GrazCosterton Biofilm Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Tim Tolker-NielsenCosterton Biofilm Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Michael GivskovCosterton Biofilm Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Katrine QvortrupDepartment of Chemistry, Technical University of Denmark, DK-2800 Lyngby, Denmark.
Funding
Sygeforsikring Danmark 2021-0300
6 · The paper itselfAbstract
This paper presents the work performed to transition a lab-scale synthesis (1 g) to a large-scale (400 g) synthesis of the 3-5-diamino-1H-Pyrazole Disperazol, a new pharmaceutical for treatment of antibiotic-resistant
Indexed as
Pseudomonas aeruginosaPyrazolesAnti-Bacterial AgentsBiofilmsHumansPseudomonas InfectionsRisk AssessmentAnti-Bacterial AgentsPyrazolesbiofilmc-di-GMPdispersaldust analysisflow chemistrylarge-scale synthesispreclinicalPseudomonas aeruginosapyrazolesafety
Identifiers
PMID38928443
PMCPMC11203405
What OpenQuestion holds
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