Evidence map›Paper›PMID 38928362›Full record

ArticleInternational journal of molecular sciences2024

Genistein Promotes M2 Macrophage Polarization via Aryl Hydrocarbon Receptor and Alleviates Intestinal Inflammation in Broilers with Necrotic Enteritis.

Shuli Quan, Jingxi Huang, Guiqin Chen, Anrong Zhang, Ying Yang, Zhenlong Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuli QuanCollege of Animal Science & Technology, China Agricultural University, Beijing 100193, China.
Jingxi HuangCollege of Animal Science & Technology, China Agricultural University, Beijing 100193, China.
Guiqin ChenCollege of Animal Science & Technology, China Agricultural University, Beijing 100193, China.
Anrong ZhangCollege of Animal Science & Technology, China Agricultural University, Beijing 100193, China.
Ying YangCollege of Animal Science & Technology, China Agricultural University, Beijing 100193, China.
Zhenlong WuCollege of Animal Science & Technology, China Agricultural University, Beijing 100193, China.

Funding

National Natural Science Foundation of China 32272899
6 · The paper itself

Abstract

The aryl hydrocarbon receptor (AhR) is a transcription factor that regulates the immune system through complicated transcriptional programs. Genistein, an AhR ligand, exhibits anti-inflammatory properties. However, its role in modulating immune responses via the AhR signaling pathway remains unclear. In this study, 360 male Arbor Acre broilers (1-day-old) were fed a basal diet supplemented with 40 or 80 mg/kg genistein and infected with or without

Indexed as

ChickensEnteritisGenisteinMacrophagesReceptors, Aryl HydrocarbonAnimalsClostridium InfectionsClostridium perfringensInflammationIntestinesMacrophage ActivationMaleMiceNecrosisPoultry DiseasesRAW 264.7 CellsGenisteinReceptors, Aryl Hydrocarbonaryl hydrocarbon receptorgenisteinintestinal inflammationM2 macrophagesnecrotic enteritis

Identifiers

PMID38928362
PMCPMC11203855

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.