Evidence map›Paper›PMID 38928283›Full record

ArticleInternational journal of molecular sciences2024

The Effect of Targeted Hyperoxemia on Brain Immunohistochemistry after Long-Term, Resuscitated Porcine Acute Subdural Hematoma and Hemorrhagic Shock.

Franziska Münz, Thomas Datzmann, Andrea Hoffmann, Michael Gröger, René Mathieu, Simon Mayer, Fabian Zink, Holger Gässler, Eva-Maria Wolfschmitt, Melanie Hogg and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Relationships Between HAntioxidants (Basel, Switzerland) · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Franziska MünzInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.
Thomas DatzmannInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.
Andrea HoffmannInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.
Michael GrögerInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.
René MathieuDepartment of Neurosurgery, German Federal Armed Forces Hospital Ulm, 89081 Ulm, Germany.
Simon MayerDepartment of Neurosurgery, German Federal Armed Forces Hospital Ulm, 89081 Ulm, Germany.
Fabian ZinkInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.ORCID 0000-0001-9458-741X
Holger GässlerDepartment of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Therapy, German Armed Forces Hospital Ulm, 89081 Ulm, Germany.ORCID 0000-0001-5610-3197
Eva-Maria WolfschmittInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.
Melanie HoggInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.
Enrico CalziaInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.ORCID 0000-0003-2663-9147
Pierre AsfarDepartment of Intensive Care and Hyperbaric Medicine, University Hospital Angers, 49045 Angers, France.
Peter RadermacherInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.
Thomas KapapaDepartment of Neurosurgery, University Hospital Ulm, 89081 Ulm, Germany.ORCID 0000-0003-1237-5347
Tamara MerzInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-5519-9171

Funding

Deutsche Forschungsgemeinschaft 251293561Deutsche Forschungsgemeinschaft 465409392
6 · The paper itself

Abstract

Epidemiological data suggest that moderate hyperoxemia may be associated with an improved outcome after traumatic brain injury. In a prospective, randomized investigation of long-term, resuscitated acute subdural hematoma plus hemorrhagic shock (ASDH + HS) in 14 adult, human-sized pigs, targeted hyperoxemia (200 < P

Indexed as

BrainHematoma, Subdural, AcuteShock, HemorrhagicAnimalsBlood-Brain BarrierDisease Models, AnimalImmunohistochemistryOxidative StressOxygenResuscitationSwineTyrosine3-nitrotyrosineOxygenTyrosineblood–brain barriercystathionine-β-synthasecystathionine-γ-lyaseoxidative/nitrosative stressoxytocinoxytocin receptortraumatic brain injury

Identifiers

PMID38928283
PMCPMC11204264

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.