Evidence map›Paper›PMID 38928277›Full record

ArticleInternational journal of molecular sciences2024

Absent in Melanoma 2 Mediates Inflammasome Signaling Activation against

Zhaoguo Ma, Yanan Lou, Na Wang, Yi Zhao, Shuxin Zhang, Mingyue Zhang, Jiaqi Li, Qian Xu, Aobo He, Shuixing Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhaoguo MaState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Yanan LouState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Na WangState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Yi ZhaoState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Shuxin ZhangState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Mingyue ZhangState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Jiaqi LiState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Qian XuState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Aobo HeState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Shuixing YuState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot 010070, China.ORCID 0009-0007-1134-1715

Funding

Inner Mongolia Engineering Technology Research Center of Germplasm Resources Conservation and Utilization No.21400-222526National Natural Science Foundation of China No.32160832National Natural Science Foundation of China No.32302886Natural Science Foundation of Inner Mongolia Autonomous Region of China No.2021BS03003Program for Young Talents of Science and Technology in Universities of Inner Mongolia Auton-omous Region of China No.NJYT22104Science and Technology Leading Talent Team in Inner Mongolia Autonomous Region of China No.2022LJRC0009Student Innovation and Entrepreneurship Training Programs of Inner Mongolia University No.21400-23269204
6 · The paper itself

Abstract

Absent in melanoma 2 (AIM2), a key component of the IFI20X/IFI16 (PYHIN) protein family, is characterized as a DNA sensor to detect cytosolic bacteria and DNA viruses. However, little is known about its immunological role during pathogenic

Indexed as

Clostridium perfringensDNA-Binding ProteinsInflammasomesSignal TransductionAnimalsClostridium InfectionsDisease Models, AnimalGas GangreneHumansImmunity, InnateMiceMice, Inbred C57BLMice, KnockoutAim2 protein, mouseDNA-Binding ProteinsInflammasomesAIM2C. perfringensgas gangreneinflammasomeinnate immune

Identifiers

PMID38928277
PMCPMC11203860

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.