ReviewInternational journal of molecular sciences2024
The Role of the Microbiota in the Pathogenesis and Treatment of Atopic Dermatitis-A Literature Review.
Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Current insights and trends in atopic dermatitis and microbiota interactions: a systematic review and bibliometric analysis.Frontiers in microbiology · 2025Pooled it
- Beyond Inflammation: The Role of Oxidative Stress and Gut-Skin Axis Dysbiosis in the Pathogenesis of Immune-Mediated Skin Disorders and Potential Therapeutic Implications.International journal of molecular sciences · 2026Review
- Effects of Prebiotic Gum Arabic Under Antibiotic-Containing Conditions in Atopic Dermatitis-Associated Bacteria: In Vitro Evaluation and Development of Semisolid Topical Carriers.Antibiotics (Basel, Switzerland) · 2026Article
- Targeting Gut Dysbiosis and Short-Chain Fatty Acid Deficiency in Chronic Eczema: A Case Report.Integrative medicine (Encinitas, Calif.) · 2026Article
- Integrative multi-omics analysis reveals gut-skin axis mechanisms and novel therapeutic targetmSystems · 2026Article
- Targeting polymicrobial skin infections in atopic dermatitis: role ofFrontiers in microbiology · 2026Article
- Impact of Dupilumab on the Skin Microbiome in Children Aged 6-12 years with Moderate-to-Severe Atopic Dermatitis.Journal of asthma and allergy · 2026Article
- From Gut Dysbiosis to Skin Inflammation in Atopic Dermatitis: Probiotics and the Gut-Skin Axis-Clinical Outcomes and Microbiome Implications.International journal of molecular sciences · 2025Review
- miRNA-146-a, miRNA-21, miRNA-143, miRNA-29-b and miRNA-223 as Potential Biomarkers for Atopic Dermatitis.Clinics and practice · 2025Article
- Extracorporeal Shock Wave Therapy (ESWT) in burn scar microbiome modulation: critical analysis of methodological rigor and translational potential.International journal of surgery (London, England) · 2025Article
- Probiotic Administration Contributes to the Improvement in Intestinal Dysregulation Induced by Allergic Contact Dermatitis.Microorganisms · 2025Article
- Immunomodulating Effects of Heat-KilledVeterinary sciences · 2025Article
- Beyond the Skin: Exploring the Gut-Skin Axis and Metabolic Pathways in Atopic Dermatitis Pathogenesis.International journal of general medicine · 2025Review
- The Neuroimmune Axis in Atopic Dermatitis: From Pathogenic Mechanisms to Targeted Neuroimmunotherapy.Journal of inflammation research · 2025Review
- Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.Frontiers in immunology · 2025Article
- Review
- The Association between Gut Microbiota and Serum Biomarkers in Children with Atopic Dermatitis.Biomedicines · 2024Article
- Gut microbiota profile and atopic dermatitis in the first year of life.Journal of medicine and life · 2024Article
- Skin microbiota: pathogenic roles and implications in atopic dermatitis.Frontiers in cellular and infection microbiology · 2024Review
- The Causal Effect Between Human Microbiota and Scabies: A Study from the Genetic Perspective.Clinical, cosmetic and investigational dermatology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atopic dermatitis (AD) is a chronic inflammatory skin condition with a high prevalence worldwide. AD pathogenesis is complex and consists of immune system dysregulation and impaired skin barrier, influenced by genetic and environmental factors. The purpose of the review is to show the complex interplay between atopic dermatitis and the microbiota. Human microbiota plays an important role in AD pathogenesis and the course of the disease. Dysbiosis is an important factor contributing to the development of atopic diseases, including atopic dermatitis. The gut microbiota can influence the composition of the skin microbiota, strengthening the skin barrier and regulating the immune response via the involvement of bacterial metabolites, particularly short-chain fatty acids, in signaling pathways of the gut-skin axis. AD can be modulated by antibiotic intake, dietary adjustments, hygiene, and living conditions. One of the promising strategies for modulating the course of AD is probiotics. This review offers a summary of how the microbiota influences the development and treatment of AD, highlighting aspects that warrant additional investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.