Evidence map›Paper›PMID 38928055›Full record

ArticleInternational journal of molecular sciences2024

Galectin-13 and Laeverin Levels Interfere with Human Fetoplacental Growth.

Márió Vincze, János Sikovanyecz, Imre Földesi, Andrea Surányi, Szabolcs Várbíró, Gábor Németh, János Sikovanyecz, Zoltan Kozinszky

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Márió VinczeDepartment of Obstetrics and Gynecology, University of Szeged, H-6725 Szeged, Hungary.
János SikovanyeczDepartment of Obstetrics and Gynecology, University of Szeged, H-6725 Szeged, Hungary.
Imre FöldesiDepartment of Laboratory Medicine, University of Szeged, H-6720 Szeged, Hungary.
Andrea SurányiDepartment of Obstetrics and Gynecology, University of Szeged, H-6725 Szeged, Hungary.ORCID 0000-0002-1168-7261
Szabolcs VárbíróDepartment of Obstetrics and Gynecology, University of Szeged, H-6725 Szeged, Hungary.
Gábor NémethDepartment of Obstetrics and Gynecology, University of Szeged, H-6725 Szeged, Hungary.
János SikovanyeczDepartment of Obstetrics and Gynecology, University of Szeged, H-6725 Szeged, Hungary.
Zoltan KozinszkyCapio Specialized Center for Gynecology, Solna, 182 88 Stockholm, Sweden.ORCID 0000-0001-7485-9895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Galectin-13 (Gal-13) is predominantly produced by the syncytiotrophoblast, while laeverin is expressed on the outgrowing extravillous trophoblast, and both are thought to be biomarkers of preeclampsia. The aim of this study was to assess the correlation between concentrations of Gal-13 and laeverin measured in maternal serum and amniotic fluid at 16-22 weeks of gestation and the sonographic assessment of the fetoplacental measurements. Fetal biometric data and placental volume and perfusion indices were measured in 62 singleton pregnancies. Serum and amniotic levels of Gal-13 and laeverin levels were measured using a sandwich ELISA. Both amniotic fluid and serum Gal-13 levels expressed a negative correlation to the plasma laeverin level in mid-pregnancy. Serum laeverin level correlated positively with the gestational length at delivery (β = 0.39,

Indexed as

Amniotic FluidGalectinsPlacentaAdultBiomarkersFemaleFetal DevelopmentGestational AgeHumansMetalloproteasesPre-EclampsiaPregnancyPregnancy ProteinsBiomarkersGalectinsLGALS13 protein, humanLVRN protein, humanMetalloproteasesPregnancy Proteinsamniotic fluidfetusGal-13humanlaeverinplacentaserumsonography

Identifiers

PMID38928055
PMCPMC11203466

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.