Evidence map›Paper›PMID 38928054›Full record

ReviewInternational journal of molecular sciences2024

Modulation of Gut Microbial Biomarkers and Metabolites in Cancer Management by Tea Compounds.

Hoi Kit Matthew Leung, Emily Kwun Kwan Lo, Fangfei Zhang, Felicianna, Marsena Jasiel Ismaiah, Congjia Chen, Hani El-Nezami

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hoi Kit Matthew LeungSchool of Biological Sciences, University of Hong Kong, Pokfulam, Hong Kong SAR 999077, China.ORCID 0009-0001-6153-7245
Emily Kwun Kwan LoSchool of Biological Sciences, University of Hong Kong, Pokfulam, Hong Kong SAR 999077, China.ORCID 0000-0001-9258-0716
Fangfei ZhangSchool of Biological Sciences, University of Hong Kong, Pokfulam, Hong Kong SAR 999077, China.
FeliciannaSchool of Biological Sciences, University of Hong Kong, Pokfulam, Hong Kong SAR 999077, China.ORCID 0000-0003-1252-5667
Marsena Jasiel IsmaiahSchool of Biological Sciences, University of Hong Kong, Pokfulam, Hong Kong SAR 999077, China.
Congjia ChenSchool of Biological Sciences, University of Hong Kong, Pokfulam, Hong Kong SAR 999077, China.ORCID 0009-0004-6800-3184
Hani El-NezamiSchool of Biological Sciences, University of Hong Kong, Pokfulam, Hong Kong SAR 999077, China.ORCID 0000-0001-6700-4346

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancers are causing millions of deaths and leaving a huge clinical and economic burden. High costs of cancer drugs are limiting their access to the growing number of cancer cases. The development of more affordable alternative therapy could reach more patients. As gut microbiota plays a significant role in the development and treatment of cancer, microbiome-targeted therapy has gained more attention in recent years. Dietary and natural compounds can modulate gut microbiota composition while providing broader and more accessible access to medicine. Tea compounds have been shown to have anti-cancer properties as well as modulate the gut microbiota and their related metabolites. However, there is no comprehensive review that focuses on the gut modulatory effects of tea compounds and their impact on reshaping the metabolic profiles, particularly in cancer models. In this review, the effects of different tea compounds on gut microbiota in cancer settings are discussed. Furthermore, the relationship between these modulated bacteria and their related metabolites, along with the mechanisms of how these changes led to cancer intervention are summarized.

Indexed as

Gastrointestinal MicrobiomeNeoplasmsTeaAnimalsBiomarkersHumansPlant ExtractsBiomarkersPlant ExtractsTeacancergut microbiotametabolitesmicrobiome targeted therapytea compounds

Identifiers

PMID38928054
PMCPMC11203446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.