Evidence map›Paper›PMID 38928005›Full record

ArticleInternational journal of molecular sciences2024

Characterization of NR1J1 Paralog Responses of Marine Mussels: Insights from Toxins and Natural Activators.

Antonio Casas-Rodríguez, Concepción Medrano-Padial, Angeles Jos, Ana M Cameán, Alexandre Campos, Elza Fonseca

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antonio Casas-RodríguezArea of Toxicology, Faculty of Pharmacy, Universidad de Sevilla, Profesor García González n◦2, 41012 Seville, Spain.
Concepción Medrano-PadialArea of Toxicology, Faculty of Pharmacy, Universidad de Sevilla, Profesor García González n◦2, 41012 Seville, Spain.ORCID 0000-0001-6358-3694
Angeles JosArea of Toxicology, Faculty of Pharmacy, Universidad de Sevilla, Profesor García González n◦2, 41012 Seville, Spain.ORCID 0000-0001-7546-3294
Ana M CameánArea of Toxicology, Faculty of Pharmacy, Universidad de Sevilla, Profesor García González n◦2, 41012 Seville, Spain.ORCID 0000-0003-1524-748X
Alexandre CamposCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal.ORCID 0000-0003-4621-885X
Elza FonsecaCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR/CIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal.ORCID 0000-0001-8955-2108

Funding

European Union-Next Generation EU and the Ministry of Universities of Spain Margarita Salas 22281/2022European Union's Horizon 2020 Marie Skłodowska-Curie grant agreements No 823860 and 101086234Portuguese Foundation for Science and Technology (Fundação para a Ciência e Tecnologia; FCT) CEECIND/03767/2018Portuguese Foundation for Science and Technology (Fundação para a Ciência e Tecnologia; FCT) and the European Regional Development Fund (ERDF) Strategic Funding UIDB/04423/2020 and UIDP/04423/2020Spanish Ministerio de Ciencia e Innovación PID 2019-104890RB-I00 MICIN/AEI/10.13039/501100011033Spanish Ministerio de Ciencia e Innovación PRE-2020-094412Spanish Ministerio de Ciencia e Innovación and European Union «NextGenerationEU»/PRTR» FJC2021-046684-I
6 · The paper itself

Abstract

The pregnane X receptor (PXR) is a nuclear hormone receptor that plays a pivotal role in regulating gene expression in response to various ligands, particularly xenobiotics. In this context, the aim of this study was to shed light on the ligand affinity and functions of four NR1J1 paralogs identified in the marine mussel

Indexed as

Marine ToxinsMytilusPregnane X ReceptorAnimalsBacterial ToxinsCyanobacteria ToxinsHumansMicroalgaeMicrocystinsXenobioticsBacterial ToxinsCyanobacteria ToxinsMarine ToxinsMicrocystinsPregnane X ReceptorXenobioticsbivalvescyanotoxinsmarine musselsmicroalgal extractsNR1J1 paralogspregnane X receptortoxins

Identifiers

PMID38928005
PMCPMC11204112

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.