Evidence map›Paper›PMID 38927968›Full record

ReviewCancers2024

The Challenging Approach to Multiple Myeloma: From Disease Diagnosis and Monitoring to Complications Management.

Sonia Morè, Laura Corvatta, Valentina Maria Manieri, Erika Morsia, Massimo Offidani

Abstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sonia MorèClinica di Ematologia Azienda Ospedaliero, Universitaria delle Marche, 60126 Ancona, Italy.
Laura CorvattaU.O.C. Medicina, Ospedale Profili, 60044 Fabriano, Italy.
Valentina Maria ManieriClinica di Ematologia Azienda Ospedaliero, Universitaria delle Marche, 60126 Ancona, Italy.
Erika MorsiaClinica di Ematologia Azienda Ospedaliero, Universitaria delle Marche, 60126 Ancona, Italy.
Massimo OffidaniClinica di Ematologia Azienda Ospedaliero, Universitaria delle Marche, 60126 Ancona, Italy.ORCID 0000-0003-2749-7347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outcome of multiple myeloma (MM) has significantly improved in the last few decades due to several factors such as new biological discoveries allowing to better stratify disease risk, development of more effective therapies and better management of side effects related to them. However, handling all these aspects requires an interdisciplinary approach involving multiple knowledge and collaboration of different specialists. The hematologist, faced with a patient with MM, must not only choose a treatment according to patient and disease characteristics but must also know when therapy needs to be started and how to monitor it during and after treatment. Moreover, he must deal not only with organ issues related to MM such as bone disease, renal failure or neurological disease but also with adverse events, often very serious, related to novel therapies, particularly new generation immunotherapies such as CAR T cell therapy and bispecific antibodies. In this review, we provide an overview on the newer MM diagnostic and monitoring strategies and on the main side effects of MM therapies, focusing on adverse events occurring during treatment with CAR T cells and bispecific antibodies.

Indexed as

bispecific antibodiesCAR T cellsinfectionmultiple myelomaside effects

Identifiers

PMID38927968
PMCPMC11202048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.