An Assessment of the Performance Limitations of the Integrated Quantifiler

Chastyn Smith, Sarah J Seashols-Williams, Edward L Boone, Tracey Dawson Green

Abstract read

In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Exploratory Study on DNA Barcode Combined with PCR-HRM Technology for Rapid and Accurate Identification of Necrophilous Fly Species.Insects · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chastyn SmithIntegrative Life Sciences, Virginia Commonwealth University, 1000 Cary Street, Richmond, VA 23284, USA.

Sarah J Seashols-WilliamsDepartment of Forensic Science, Virginia Commonwealth University, 1015 Floyd Avenue, Richmond, VA 23284, USA.ORCID 0000-0003-0093-8261

Edward L BooneDepartment of Statistical Sciences & Operations Research, Virginia Commonwealth University, 1015 Floyd Avenue, Richmond, VA 23284, USA.ORCID 0000-0003-0755-6899

Tracey Dawson GreenDepartment of Forensic Science, Virginia Commonwealth University, 1015 Floyd Avenue, Richmond, VA 23284, USA.ORCID 0000-0003-4761-6657

Funding

National Institute of Justice 2019-DU-BX-0003

6 · The paper itself

Abstract

Although guidelines exist for identifying mixtures, these measures often occur at the end-point of analysis and are protracted. To facilitate early mixture detection, we integrated a high-resolution melt (HRM) mixture screening assay into the qPCR step of the forensic workflow, producing the integrated Quantifiler

Indexed as

Forensic GeneticsDNADNA FingerprintingHumansMicrosatellite RepeatsReal-Time Polymerase Chain ReactionReproducibility of ResultsDNAdevelopmental validationforensic samplesHRMmixture screeningprediction modelingqPCR

Identifiers

PMID38927704

DOI10.3390/genes15060768

PMCPMC11202460

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.