Evidence map›Paper›PMID 38927677›Full record

ArticleGenes2024

Utilization of qPCR to Determine Duration and Environmental Drivers Contributing to the Persistence of Human DNA in Soil.

Hannah L Noel, Rebecca L George, Brittania Bintz, Maureen Peters Hickman, Frankie West

Abstract read
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hannah L NoelDepartment of Microbiology, University of Tennessee, Knoxville, TN 37996, USA.ORCID 0009-0004-1360-5698
Rebecca L GeorgeDepartment of Anthropology and Sociology, Western Carolina University, Cullowhee, NC 29723, USA.ORCID 0000-0002-3901-1677
Brittania BintzDepartment of Chemistry and Physics, Forensic Science Program, Western Carolina University, Cullowhee, NC 29723, USA.
Maureen Peters HickmanDepartment of Biology, Western Carolina University, Cullowhee, NC 29723, USA.
Frankie WestDepartment of Chemistry and Physics, Forensic Science Program, Western Carolina University, Cullowhee, NC 29723, USA.ORCID 0000-0002-8625-4452

Funding

Western Carolina University Forensic Science ProgramWestern Carolina University Summer Graduate Research Assistantship
6 · The paper itself

Abstract

Little is known about the underlying mechanisms that contribute to the persistence and degradation of DNA within soil. The goals of this study are to determine the duration of mitochondrial DNA (mtDNA) and nuclear DNA (nuDNA) persistence in soils enriched by surface-level human decomposition and to better understand the contribution of environmental factors. The surface-level decomposition of three human cadavers was documented over 11 weeks. Based on quantitative PCR results, we found nuDNA to persist in soils six weeks post-placement, while mtDNA was recoverable for the entire 11-week decomposition period. Principle components analyses and Spearman's rank correlations revealed that (1) time, (2) total body score, and (3) weekly average air temperature were significantly correlated with concentrations of nuDNA and mtDNA in soil, suggesting these factors play a role in the degradation of DNA in soils.

Indexed as

DNA, MitochondrialSoilCadaverDNAHumansReal-Time Polymerase Chain ReactionDNADNA, MitochondrialSoilDNA degradationDNA persistencehuman decompositionquantitative PCRsoil taphonomy

Identifiers

PMID38927677
PMCPMC11202937

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.