Evidence map›Paper›PMID 38927607›Full record

ReviewGenes2024

Cardiac Remodeling and Ventricular Pacing: From Genes to Mechanics.

Onoufrios Malikides, Emmanouel Simantirakis, Evangelos Zacharis, Konstantinos Fragkiadakis, George Kochiadakis, Maria Marketou

Abstract readReview
In one paragraph

Review in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Onoufrios MalikidesDepartment of Cardiology, University General Hospital of Heraklion, 71003 Heraklion, Greece.ORCID 0009-0008-1691-644X
Emmanouel SimantirakisDepartment of Cardiology, University General Hospital of Heraklion, 71003 Heraklion, Greece.
Evangelos ZacharisDepartment of Cardiology, University General Hospital of Heraklion, 71003 Heraklion, Greece.
Konstantinos FragkiadakisDepartment of Cardiology, University General Hospital of Heraklion, 71003 Heraklion, Greece.ORCID 0000-0002-5342-5411
George KochiadakisDepartment of Cardiology, University General Hospital of Heraklion, 71003 Heraklion, Greece.
Maria MarketouDepartment of Cardiology, University General Hospital of Heraklion, 71003 Heraklion, Greece.ORCID 0000-0003-1888-3430

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac remodeling and ventricular pacing represent intertwined phenomena with profound implications for cardiovascular health and therapeutic interventions. This review explores the intricate relationship between cardiac remodeling and ventricular pacing, spanning from the molecular underpinnings to biomechanical alterations. Beginning with an examination of genetic predispositions and cellular signaling pathways, we delve into the mechanisms driving myocardial structural changes and electrical remodeling in response to pacing stimuli. Insights into the dynamic interplay between pacing strategies and adaptive or maladaptive remodeling processes are synthesized, shedding light on the clinical implications for patients with various cardiovascular pathologies. By bridging the gap between basic science discoveries and clinical translation, this review aims to provide a comprehensive understanding of cardiac remodeling in the context of ventricular pacing, paving the way for future advancements in cardiovascular care.

Indexed as

Ventricular RemodelingAnimalsCardiac Pacing, ArtificialHeart VentriclesHumanscardiac remodelingpacing

Identifiers

PMID38927607
PMCPMC11203142

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.