Evidence map›Paper›PMID 38927541›Full record

ReviewBiomedicines2024

The Importance of Sleep in Overcoming Childhood Obesity and Reshaping Epigenetics.

Erika Richter, Priyadarshni Patel, Jeganathan Ramesh Babu, Xu Wang, Thangiah Geetha

Abstract readReview
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erika RichterDepartment of Nutritional Sciences, Auburn University, Auburn, AL 36849, USA.ORCID 0009-0009-5867-5231
Priyadarshni PatelDepartment of Nutritional Sciences, Auburn University, Auburn, AL 36849, USA.
Jeganathan Ramesh BabuDepartment of Nutritional Sciences, Auburn University, Auburn, AL 36849, USA.
Xu WangAlabama Agricultural Experiment Station, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-7594-5004
Thangiah GeethaDepartment of Nutritional Sciences, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0001-6358-0012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of childhood obesity is a complex process influenced by a combination of genetic predisposition and environmental factors, such as sleep, diet, physical activity, and socioeconomic status. Long-term solutions for decreasing the risk of childhood obesity remain elusive, despite significant advancements in promoting health and well-being in school and at home. Challenges persist in areas such as adherence to interventions, addressing underlying social determinants, and individual differences in response to treatment. Over the last decade, there has been significant progress in epigenetics, along with increased curiosity in gaining insights into how sleep and lifestyle decisions impact an individual's health. Epigenetic modifications affect the expression of genes without causing changes to the fundamental DNA sequence. In recent years, numerous research studies have explored the correlation between sleep and the epigenome, giving a better understanding of DNA methylation, histone modification, and non-coding RNAs. Although significant findings have been made about the influence of sleep on epigenetics, a notable gap exists in the literature concerning sleep-related genes specifically associated with childhood obesity. Consequently, it is crucial to delve deeper into this area to enhance our understanding. Therefore, this review primarily focuses on the connection between sleep patterns and epigenetic modifications in genes related to childhood obesity. Exploring the interplay between sleep, epigenetics, and childhood obesity can potentially contribute to improved overall health outcomes. This comprehensive review encompasses studies focusing on sleep-related genes linked to obesity.

Indexed as

childhood obesityDNA methylationepigeneticshistone modificationsnon-coding RNAssleep

Identifiers

PMID38927541
PMCPMC11201669

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.