ReviewBiomedicines2024
Management of Fibromyalgia: An Update.
Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of randomized controlled trials evaluating the effect of whole body vibration training on fibromyalgia.Scientific reports · 2025Pooled it
- Transcutaneous Electrical Nerve Stimulation and Pain With Movement in People With Fibromyalgia: A Cluster Randomized Clinical Trial.JAMA network open · 2026Trial
- The effect of blood flow restricted aerobic exercise training on pain, functional status, quality of life and hormonal response to exercise in fibromyalgia patients: a randomized double-blind study.European journal of physical and rehabilitation medicine · 2025Trial
- The Impact of Standard Care Versus Intrinsic Relaxation at Home on Physiological Parameters in Patients with Fibromyalgia: A Comparative Cohort Study from Romania.Medicina (Kaunas, Lithuania) · 2025Trial
- "This is how we should work" - healthcare professionals' past uncertainty and present confidence in management of fibromyalgia.International journal of qualitative studies on health and well-being · 2026Article
- Effects ofPain reports · 2026Article
- The Role of Behavioral and Psychological Interventions in Chronic Ocular Pain.Current pain and headache reports · 2026Review
- Therapeutic and research frontiers in fibromyalgia: integrating pathophysiology with innovative drug repurposing.Inflammopharmacology · 2026Review
- Sublingual Cyclobenzaprine for Fibromyalgia: Pharmacokinetic Rationale, Clinical Evidence, and Place in Therapy.Current pain and headache reports · 2026Review
- Sociodemographic Factors, but Not Rurality, Explain Limited Variance in Fibromyalgia Severity: A Secondary Analysis of Two Randomized Clinical Trials.Pain medicine (Malden, Mass.) · 2026Article
- Sublingual Cyclobenzaprine Approval: Expanding Options for Fibromyalgia Management.Health science reports · 2026Article
- Investigation of the Effectiveness of Mindfulness-Based Yoga Training in Individuals with Fibromyalgia: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2026Article
- Fibromyalgia in systemic autoimmune rheumatic diseases: a mixed-methods study of patient and clinician perspectives.Rheumatology international · 2026Article
- The expanding potential of low-dose naltrexone in clinical practice with a focus on long COVID.The mental health clinician · 2026Article
- Fibromyalgia: A Multifactorial Pain Disorder.International journal of molecular sciences · 2026Review
- Kinesiophobia and Work Disability in Fibromyalgia: Cognitive Mediation in a Population-Based Study of Women.European journal of investigation in health, psychology and education · 2026Article
- Effects of Physical Exercise on Anxiety and Depression of People with Fibromyalgia: Umbrella Review of Systematic Reviews and Meta-Analyses.Journal of functional morphology and kinesiology · 2026Review
- Article
- BDNF and IL-33 Dynamics in an Ultrasound Stress Model of Fibromyalgia-like Phenotypes.International journal of molecular sciences · 2026Article
- Immersive Virtual Reality Exercise: Effects on Cortisol, Quality of Life, Cognitive Function, and Psychological Symptoms in Fibromyalgia.Medicina (Kaunas, Lithuania) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibromyalgia, a chronic pain condition marked by abnormal pain processing, impacts a significant part of the population, leading to reduced quality of life and function. Hallmark symptoms include widespread persistent pain, sleep disturbances, fatigue, cognitive dysfunction, and mood changes. Through this updated review, we aim to contribute to the evolving understanding and management of fibromyalgia, offering insights into the diverse tools available to improve the lives of those affected by this challenging condition. Management begins with educating patients to ultimately relieve them of unnecessary testing and provide reassurance. Treatment emphasizes a comprehensive approach, combining nonpharmacological interventions such as aforementioned education, exercise, and psychotherapy, alongside pharmacologic management-namely duloxetine, milnacipran, pregabalin, and amitriptyline-which have consistent benefits for a range of symptoms across the spectrum of fibromyalgia. Notably, drugs like nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen are generally not recommended due to limited efficacy and associated risks. Lastly, a variety of other medications have shown promise, including NMDA-receptor antagonists, naltrexone, and cannabinoids; however, they should be used with caution due to a small amount of evidence and potential for adverse effects.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.