Evidence map›Paper›PMID 38927389›Full record

ArticleBiomedicines2024

Joint Effects of Exercise and Ramadan Fasting on Telomere Length: Implications for Cellular Aging.

Shamma Almuraikhy, Maha Sellami, Khaled Naja, Hadaia Saleh Al-Amri, Najeha Anwardeen, Amina Aden, Alexander Dömling, Mohamed A Elrayess

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shamma AlmuraikhyBiomedical Research Center, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-4572-9738
Maha SellamiPhysical Education Department (PE), College of Education, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-1832-409X
Khaled NajaBiomedical Research Center, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0001-9259-3082
Hadaia Saleh Al-AmriPhysical Education Department (PE), College of Education, Qatar University, Doha P.O. Box 2713, Qatar.
Najeha AnwardeenBiomedical Research Center, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0002-7263-4905
Amina AdenHamad Medical Corporation (HMC), Doha P.O. Box 3050, Qatar.
Alexander DömlingGroningen Research Institute of Pharmacy, Drug Design, Groningen University, 9712 CP Groningen, The Netherlands.ORCID 0000-0002-9923-8873
Mohamed A ElrayessBiomedical Research Center, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-3803-4604

Funding

Qatar University IRCC-2022-467
6 · The paper itself

Abstract

Aging is a fundamental biological process that progressively impairs the functionality of the bodily systems, leading to an increased risk of diseases. Telomere length is one of the most often used biomarkers of aging. Recent research has focused on developing interventions to mitigate the effects of aging and improve the quality of life. The objective of this study was to investigate the combined effect of exercise and Ramadan fasting on telomere length. Twenty-nine young, non-obese, healthy females were randomized into two groups: the control group underwent a 4-week exercise training program, and the second group underwent a 4-week exercise training program while fasting during Ramadan. Blood samples were collected, and measurements of clinical traits, cytokines, oxidative stress, and telomere length were performed before and after intervention. Telomere length increased significantly from baseline in the exercise-while-fasting group, but showed no significant change in the exercise control group. This increase was accompanied by a reduction in TNF-α, among other cytokines. Additionally, a significant positive correlation was observed between the mean change in telomere length and HDL in the exercise-while-fasting group only. This study is the first to report an increase in telomere length after combining Ramadan fasting with training, suggesting that exercising while fasting may be an effective tool for slowing down the aging rate. Further studies using larger and more diverse cohorts are warranted.

Indexed as

biomarkersexercisehuman agingRamadan fastingtelomere length

Identifiers

PMID38927389
PMCPMC11200901

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.