Evidence map›Paper›PMID 38927382›Full record

ArticleBiomedicines2024

Machine Learning Model in Obesity to Predict Weight Loss One Year after Bariatric Surgery: A Pilot Study.

Enrique Nadal, Esther Benito, Ana María Ródenas-Navarro, Ana Palanca, Sergio Martinez-Hervas, Miguel Civera, Joaquín Ortega, Blanca Alabadi, Laura Piqueras, Juan José Ródenas and 1 more

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Enrique NadalInstituto Universitario de Ingeniería Mecánica y Biomecánica (I2MB), Universitat Politècnica de València, 46022 Valencia, Spain.ORCID 0000-0002-2808-298X
Esther BenitoCIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), 28040 Madrid, Spain.ORCID 0000-0003-3445-2913
Ana María Ródenas-NavarroEndocrinology and Nutrition Service, Clinical University Hospital of Valencia, 46010 Valencia, Spain.
Ana PalancaEndocrinology and Nutrition Service, Clinical University Hospital of Valencia, 46010 Valencia, Spain.ORCID 0000-0003-3513-4458
Sergio Martinez-HervasCIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), 28040 Madrid, Spain.ORCID 0000-0002-6775-2034
Miguel CiveraEndocrinology and Nutrition Service, Clinical University Hospital of Valencia, 46010 Valencia, Spain.
Joaquín OrtegaINCLIVA Biomedical Research Institute, 46010 Valencia, Spain.ORCID 0000-0001-7126-0780
Blanca AlabadiCIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), 28040 Madrid, Spain.ORCID 0000-0001-5129-6954
Laura PiquerasCIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), 28040 Madrid, Spain.
Juan José RódenasInstituto Universitario de Ingeniería Mecánica y Biomecánica (I2MB), Universitat Politècnica de València, 46022 Valencia, Spain.ORCID 0000-0003-2195-7920
José T RealCIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), 28040 Madrid, Spain.

Funding

Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas AsociadasCIBER de Bioingenieria, Biomateriales y NanomaterialesGeneralitat Valenciana AICO 2019/250Instituto de Salud Carlos III PI15/00082Instituto de Salud Carlos III PI18/00209Instituto de Salud Carlos III PIE15/00013Ministerio de Economía, Industria y Competitividad DPI2017-89816-RMinisterio de Economía, Industria y Competitividad SAF2014-57845-R
6 · The paper itself

Abstract

Roux-en-Y gastric bypass (RYGB) is a treatment for severe obesity. However, many patients have insufficient total weight loss (TWL) after RYGB. Although multiple factors have been involved, their influence is incompletely known. The aim of this exploratory study was to evaluate the feasibility and reliability of the use of machine learning (ML) techniques to estimate the success in weight loss after RYGP, based on clinical, anthropometric and biochemical data, in order to identify morbidly obese patients with poor weight responses. We retrospectively analyzed 118 patients, who underwent RYGB at the Hospital Clínico Universitario of Valencia (Spain) between 2013 and 2017. We applied a ML approach using local linear embedding (LLE) as a tool for the evaluation and classification of the main parameters in conjunction with evolutionary algorithms for the optimization and adjustment of the parameter model. The variables associated with one-year postoperative %TWL were obstructive sleep apnea, osteoarthritis, insulin treatment, preoperative weight, insulin resistance index, apolipoprotein A, uric acid, complement component 3, and vitamin B12. The model correctly classified 71.4% of subjects with TWL < 30% although 36.4% with TWL ≥ 30% were incorrectly classified as "unsuccessful procedures". The ML-model processed moderate discriminatory precision in the validation set. Thus, in severe obesity, ML-models can be useful to assist in the selection of patients before bariatric surgery.

Indexed as

bariatric surgerylocally linear embeddingmachine learningobesitypredictive modelRYGBtotal weight loss

Identifiers

PMID38927382
PMCPMC11200726

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.