Evidence map›Paper›PMID 38927159›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Halicin: A New Horizon in Antibacterial Therapy against Veterinary Pathogens.

Shuge Wang, Ke Zhao, Ziqi Chen, Dejun Liu, Shusheng Tang, Chengtao Sun, Hongliang Chen, Yang Wang, Congming Wu

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Repurposing Birabresib to target Gram‑positive bacteria.npj antimicrobials and resistance · 2026
    Article
  3. Article
  4. Article
  5. Frontiers in bioinformatics · 2026
    Review
  6. Review
  7. Review
  8. In Vivo Effect of Halicin on Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuge WangNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China.
Ke ZhaoNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China.
Ziqi ChenNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China.
Dejun LiuNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China.
Shusheng TangNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China.
Chengtao SunNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China.ORCID 0000-0003-0083-8877
Hongliang ChenSchool of Life Sciences, Xiamen University, Xiamen 361005, China.
Yang WangNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China.
Congming WuNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China.

Funding

Guangdong Major Project of Basic and Applied Basic Research Grant No. 2020B0301030007Pinduoduo-China Agricultural University Research Fund Grant No. PC2023A01002
6 · The paper itself

Abstract

It is crucial to discover novel antimicrobial drugs to combat resistance. This study investigated the antibacterial properties of halicin (SU3327), an AI-identified anti-diabetic drug, against 13 kinds of common clinical pathogens of animal origin, including multidrug-resistant strains. Employing minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) assessments, halicin demonstrated a broad-spectrum antibacterial effect. Time-killing assays revealed its concentration-dependent bactericidal activity against

Indexed as

halicinin vitro and in vivo antibacterial efficacyPAEPA-SMEpathogenic bacteriatoxicityveterinary medicine

Identifiers

PMID38927159
PMCPMC11200678

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.